垂体瘤患者经鼻中隔黏膜下入路切除术后嗅觉改变的相关危险因素分析  

Analysis of risk factors for olfactory changes after transseptal submucosal resection in patients with pituitary tumor

作　　者：彭艳媛 王丽雯 罗丽[1] Peng Yanyuan;Wang Liwen;Luo Li(The Second Affiliated Hospital of Nanchang University,Nanchang,Jiangxi 330000,China)

机构地区：[1]南昌大学第二附属医院,江西南昌330000

出　　处：《首都食品与医药》2023年第2期21-23,共3页Capital Food Medicine

摘　　要：目的分析垂体瘤患者经鼻中隔黏膜下入路切除术后嗅觉改变的相关危险因素.方法回顾性分析,收集2020年4月-2022年5月南昌大学第二附属医院收治的35例经鼻中隔黏膜下入路切除术后发生嗅觉改变的垂体瘤患者病例资料,纳入改变组;另收集同期该医院收治的35例经手术治疗后未发生嗅觉改变的垂体瘤患者病例资料,纳入未改变组;查阅并记录患者相关资料,经Logistics回归分析垂体瘤患者术后嗅觉改变的相关危险因素.结果改变组术中切除中鼻甲、术后并发症发生率、嗅觉附属区损伤、早期未进行嗅觉刺激占比均高于未改变组,差异有统计学意义(P<0.05);两组患者其他基线资料比较,差异无统计学意义(P>0.05);经Logistics回归分析,结果显示,术中切除中鼻甲、术后并发症、嗅觉附属区损伤、早期未进行嗅觉刺激均为垂体瘤患者术后嗅觉改变的相关危险因素(P<0.05).结论垂体瘤患者切除术后嗅觉改变可能受切除中鼻甲、术后并发症、嗅觉附属区损伤、早期未进行嗅觉刺激等因素影响.Objective To analyze the risk factors of olfactory changes in patients with pituitary tumor after transnasal septal submucosal approach.Methods From April 2020 to May 2022,35 patients with pituitary tumor with olfactory changes after transnasal septal submucosal approach in our hospital were retrospectively analyzed and included in the change group.In addition,35 patients with pituitary tumor who did not have olfactory changes afer surgical treatment in the same period were included in the unchanged group.The relevant data of patients were reviewed and recorded,and the risk factors of postoperative olfactory changes in patients with pituitary tumor were analyzed by Logistics regression.Results The incidence of intraoperative resection of middle turbinate,postoperative complications,olfactory accessory area injury,and the proportion of early olfactory stimulation in the change group were higher than those in the unchanged group(P<0.05).There was no significant difference in other baseline data between the two groups(P>0.05).Logistics regression analysis showed that intraoperative resection of middle turbinate,postoperative complications,olfactory accessory area injury,and early absence of olfactory stimulation were all risk factors for postoperative olfactory changes in patients with pituitary tumor(P<0.05).Conc lus ions Olfactory changes after pituitary tumor resection may be affected by middle turbinate resection,postoperative complications,olfactory accessory area injury,early failure to perform olfactory stimulation and other factors.

关 键 词：垂体瘤 经鼻中隔黏膜下入路切除术 嗅觉改变 早期未嗅觉刺激 切除中鼻甲 术后并发症 嗅觉附属区损伤 

分 类 号：R739.41[医药卫生—肿瘤]