探讨导水管面积及ROI大小对PC-MRI流量检测的影响  

Influence of Aqueduct Area and Region of Interest Size on Quantification of Stroke Volume in Healthy Volunteers Using Phase Contrast Cine MRI

作　　者：彭静华[1] 杨海鑫 孟磊[2] 郭孝龙[2] 李小潘[3] 张鸿日[2] PENG Jing-hua;YANG Hai-xin;MENG Lei;GUO Xiao-long;LI Xiao-pan;ZHANG Hong-ri(Department of Neurology,The First Affiliated Hospital,and College of Clinical Medicine of Henan University of Science and Technology,Luoyang 471000,Henan Province,China;Department of Neurosurgery,The First Affiliated Hospital,and College of Clinical Medicine of Henan University of Science and Technology,Luoyang 471000,Henan Province,China;Department of Radiology,The First Affiliated Hospital,and College of Clinical Medicine of Henan University of Science and Technology,Luoyang 471000,Henan Province,China)

机构地区：[1]河南科技大学第一附属医院神经内科,河南洛阳471000 [2]河南科技大学第一附属医院神经外科,河南洛阳471000 [3]河南科技大学第一附属医院影像中心,河南洛阳471000

出　　处：《中国CT和MRI杂志》2023年第3期22-24,共3页Chinese Journal of CT and MRI

基　　金：河南省高端人才国际化培养项目(0120180099);河南省医学科技攻关省部共建项目(SB201901066)。

摘　　要：目的探讨中脑导水管面积、感兴趣区域(ROI)大小对脑脊液(CSF)流量检测的影响。方法19名志愿者纳入研究,3.0-T磁共振,手动ROI放置对导水管CSF流量定量分析,比较5、10、15mm2大小ROI检测CSF流量的结果(对应为SV5、SV10、SV15)。心动周期内进行12次扫描,测量导水管不同时间点的面积并进行分析。依据不同面积设计新方法计算流量(SVtotal),与常规方法检测的流量(SVnormal)进行比较。结果SV5显著低于SV10(0.003±0.002 m L vs.0.0057±0.0025 m L,P=0.031)和SV15(0.0068±0.0034m L,P=0.035)。心动周期内导水管的面积存在差别(P=0.01),SVTotal显著低于SVNomal(0.005±0.003m L vs.0.0069±0.0027 m L,P=0.023)。结论中脑导水管面积变化、ROI面积对CSF流量的检测有影响。Objective To assess the influence of the area and the region of interest(ROI)in quantifying the aqueductal stroke volume(SV)measured with phase-contrast magnetic resonance imaging(PCMRI)within the cerebral aqueduct at the level of the intercollicular sulcus.Methods Ninteen healthy volunteers(mean age 29.6 years)were enrolled in the study,and brain MRI examinations were performed on a 3.0-T system.Quantitative analysis of the aqueductal cerebrospinal fluid(CSF)flow was performed using manual ROI placement.ROIs were separately drawn for each of the 12 phases of the cardiac cycle,and changes in aqueduct size during the cardiac cycle were determined.The SV was calculated using 12 different aqueductal ROIs and compared with the SV calculated using a fixed ROI size.Results There was variation in the size of the aqueduct during the cardiac cycle was noted.In addition,the measured SV increased with a greater area of the ROI.A significant difference in the calculated SVs with the 12 variable ROIs was observed compared with that using a fixed ROI throughout the cardiac cycle.Conclusion The study results indicate a variation in the size of the cerebral aqueduct,which is used to calculate the SV during the cardiac cycle.To establish reliable reference values for the SV in future studies,a variable ROI should be considered and incorporated to account for cardiac cycle variations.

关 键 词：脑脊液 中脑导水管 核磁共振 脑脊液电影 感兴趣区域 流量 

分 类 号：R445.2[医药卫生—影像医学与核医学]