A tRF oligomerizes Nucleolin to stabilize metastasis-favoring transcripts  

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作  者:Jiawei Guo Yong Peng 

机构地区:[1]Laboratory of Molecular Oncology, Frontiers Science Center for Disease-related Molecular Network, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

出  处:《Science China(Life Sciences)》2023年第3期646-648,共3页中国科学(生命科学英文版)

基  金:supported by the National Natural Science Foundation of China(82273168);the Science and Technology Foundation of Sichuan Province,China(2022YFS0046);the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(ZYGD20008)。

摘  要:Apart from bringing amino acids to ribosomes for protein biogenesis,transfer RNA(t RNA)can be cleaved into small non-coding RNAs,named as t RFs or ts RNAs.These small RNA fragments were firstly thought as random degradation products of t RNAs until the induction of certain t RFs were observed in specific stress conditions(Li et al.,2008).

关 键 词:METASTASIS bringing 

分 类 号:Q24[生物学—细胞生物学]

 

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