手性环戊二烯配体及其金属配合物的合成研究进展  

Advances in the synthesis of chiral cyclopentadienyl ligands and metal complexes

作　　者：杨慧 苟博博 戴昊天 顾庆[1] 游书力[1] Hui Yang;Bo-Bo Gou;Hao-Tian Dai;Qing Gu;Shu-Li You(State Key Laboratory of Organometallic Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200232,China)

机构地区：[1]中国科学院上海有机化学研究所,金属有机化学国家重点实验室,上海200232

出　　处：《中国科学：化学》2023年第3期359-374,共16页SCIENTIA SINICA Chimica

基　　金：国家自然科学基金(编号:91856201,22071260);国家重点研发计划(编号:2021YFA1500100)资助项目。

摘　　要：环戊二烯基负离子能与金属形成稳定的配合物,在金属催化反应中有着广泛的应用.随着不对称催化反应的快速发展,一系列具有不同骨架的手性环戊二烯配体被相继报道.与此同时,相应的金属配合物也被广泛应用于不对称金属催化反应中.本文综述了手性环戊二烯配体及其金属配合物的合成研究,介绍了手性环戊二烯金属配合物在不对称C–H键官能团化反应中的应用,同时探讨了该领域当前研究所面临的机遇与挑战.Cyclopentadienyl(Cp)metal complexes have been widely used as efficient catalysts in homogeneous catalysis.The emergence of novel chiral cyclopentadienyl ligands has accelerated the development of transition-metalcatalyzed asymmetric reactions.Since 2012,various chiral Cp ligands and their transition-metal complexes have been synthesized and used in a diverse array of reactions.In this review,we summarize the design and syntheses of chiral cyclopentadienyl ligands and their metal complexes,and briefly describe their applications in asymmetric C–H functionalization reactions.In addition,the opportunities and challenges on the synthesis and application of cyclopentadienyl ligands in asymmetric catalysis are discussed.

关 键 词：不对称催化 手性配体 环戊二烯基 金属配合物 

分 类 号：O641.4[理学—物理化学] O621.251[理学—化学]