卵巢癌一级预防研究进展  

Primary Prevention of Ovarian Cancer

作　　者：沈丽娜 臧荣余[1] SHEN Li’na;ZANG Rongyu(Department of Gynecologic Oncology,Zhongshan Hospital,Fudan University,Shanghai 200032,China)

机构地区：[1]复旦大学附属中山医院妇科肿瘤科,上海200032

出　　处：《肿瘤防治研究》2023年第3期224-228,共5页Cancer Research on Prevention and Treatment

基　　金：国家自然科学基金(81972429);上海市科委医学创新研究专项(22Y21900300)。

摘　　要：卵巢癌是严重危害女性健康的恶性肿瘤之一,其死亡率居妇科恶性肿瘤首位。目前遗传易感是卵巢癌较明确的高危因素,其他可能的因素包括激素使用、疾病/生殖相关因素及生活方式等。根据卵巢癌发生的不同风险等级,可将人群分为高风险人群和普通人群,本文就两个人群的筛查策略、干预措施两方面分别进行研究进展追踪。常规筛查不能提高普通人群卵巢癌的检出率,也无法提高卵巢癌生存。加强卵巢癌高风险人群肿瘤预防意识,进行有效筛查及干预,是降低卵巢癌发病率及死亡率的重要手段。Ovarian cancer is the most lethal malignancy of the female genital tract.Genetic predisposition,usage of hormone,relative disease and reproduction,and lifestyle factors are possible risk factors for ovarian cancer.Women can be stratified into high risk and general populations according to the ovarian cancer risk.Screening and prevention were reviewed for the two populations.Population-based trials in the general population have not demonstrated that screening improves early detection or survival.Strengthening the awareness of tumor prevention and conducting effective screening and prevention in the high-risk population are cost-effective methods to reduce the incidence and mortality of ovarian cancer.

关 键 词：卵巢癌 一级预防 筛查 

分 类 号：R737.31[医药卫生—肿瘤]