正常眼压性青光眼24小时眼压波动的研究进展  

Research progress of 24-hour intraocular pressure fluctuation in normal-tension glaucoma

作　　者：苏涤菲 卿国平[1] Su Difei;Qing Guoping(Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Key Laboratory of Ophthalmology and Visual Science,Beijing 100730,China)

机构地区：[1]首都医科大学附属北京同仁医院、北京同仁眼科中心、眼科学与视觉科学北京市重点实验室,100730

出　　处：《国际眼科纵览》2023年第1期24-29,共6页International Review of Ophthalmology

摘　　要：正常眼压性青光眼(normal-tension glaucoma,NTG)是一种慢性进行性视神经病变,发病时眼压在正常范围内。NTG在开角型青光眼中的占比较高。在NTG的诊断中,24 h眼压测量尤其重要,是与原发性开角型青光眼相鉴别的主要体征。NTG患者24 h眼压监测通常表现为夜间出现眼压峰值,且其眼压的昼夜波动幅度往往比正常人大。且24 h眼压的平均眼压、短期和长期眼压波动幅度、最小眼压值都显示为NTG疾病进展中的预测参数。这使得NTG患者24 h眼压监测及根据其24 h眼压波动特点进行个体化治疗变得尤为重要。Normal-tension glaucoma(NTG)is a chronic progressive optic neuropathy,in which the intraocular pressure(IOP)is within the normal range.More and more evidence shows that NTG accounts for a high proportion of open-angle glaucoma.In the diagnosis of NTG,24-hour IOP measurement is particularly important,and it is the main sign to differentiate NTG from POAG.The 24-hour IOP monitoring of NTG patients usually shows peak intraocular pressure at night,and the diurnal fluctuation of IOP is often larger than normal.In addition,the average IOP,short-term and long-term IOP fluctuation amplitude and minimum IOP value of 24 h IOP are all the predictive parameters of NTG disease progression.This makes the 24-hour IOP monitoring of NTG patients and individualized treatment based on the characteristics of their 24-hour IOP fluctuation become particularly important.

关 键 词：正常眼压性青光眼 原发性开角型青光眼 眼压波动 

分 类 号：R775[医药卫生—眼科]