超声引导下真空辅助旋切手术治疗乳腺良性叶状肿瘤疗效及术后局部复发危险因素分析  

Clinical efficacy of ultrasound-guided vacuum-assisted excision in the treatment of breast benign phyllode tumor and the risk factors of local recurrence after operation

作　　者：马俊强 侯晓克 郭强 牛钊峰 Ma Junqiang;Hou Xiaoke;Guo Qiang;Niu Zhaofeng(Department of Breast Surgery,Yuncheng Central Hospital,Yuncheng 044000,China)

机构地区：[1]运城市中心医院乳腺外科,运城044000

出　　处：《国际外科学杂志》2023年第2期93-97,共5页International Journal of Surgery

摘　　要：目的探讨超声引导下真空辅助旋切(VAE)手术治疗乳腺良性叶状肿瘤疗效及术后局部复发危险因素。方法采用回顾性研究方法,纳入2012年1月—2020年1月运城市中心医院收治的乳腺良性叶状肿瘤患者共256例,均为女性,其中160例采用超声引导下VAE手术治疗,96例采用开放手术治疗。计量资料以均数±标准差(±s)表示,组间比较采用t检验;计数资料组间比较采用χ^(2)检验或Fisher确切概率法;乳腺良性叶状肿瘤术后局部复发有关影响因素先进行单因素分析,然后将单因素分析中差异有统计学意义的因素进一步纳入多因素Logistic回归分析。结果单因素分析结果显示,肿瘤最大径≥25 mm和既往同侧乳房纤维腺瘤疾病史与乳腺良性叶状肿瘤术后局部复发有关(P<0.05);多因素Logistic回归分析结果显示,肿瘤最大径≥25 mm是乳腺良性叶状肿瘤术后局部复发的独立危险因素(P<0.05)。结论超声引导下VAE手术可降低最大径<25 mm的乳腺良性叶状肿瘤术后局部复发率;肿瘤最大径≥25 mm往往预示患者术后高局部复发风险。Objective To investigate the clinical efficacy of ultrasound-guided vacuum-assisted excision(VAE)in the treatment of breast benign phyllode tumor and the risk factors of local recurrence after operation.Methods A total of 256 cases of patients with breast benign phyllode tumor admitted to Yuncheng Central Hospital from January 2012 to January 2020 were included in the retrospective study,they were all female,of which 160 cases received ultrasound-guided VAE surgical treatment and 96 cases received open surgical treatment.Measurement data were expressed as mean±standard deviation(x±s),and t-test was used for comparison between groups.The Chi-square test or Fisher exact probability method was used to compare the data groups.Univariate analysis was performed on the factors related to the local recurrence of benign phyllode tumor after surgery,and then the factors with statistically significant differences in the univariate analysis were further incorporated into multivariate Logistic regression analysis.Results Univariate analysis results showed that the maximum diameter of tumor≥25 mm and the history of ipsilateral breast fibroadenoma were associated with postoperative local recurrence of breast benign phyllodes tumor(P<0.05).Multivariate Logistic regression analysis results showed that tumor diameter≥25 mm was an independent risk factor for postoperative local recurrence of breast benign phyllodes tumor(P<0.05).Conclusion Ultrasound-guided VAE in the treatment of breast benign phyllodes tumor patients with maximum diameter less than 25 mm can reduce the postoperative local recurrence rate,and patients with tumor maximum diameter greater than 25 mm should have the higher local recurrence risk.

关 键 词：乳腺肿瘤 外科手术 复发 叶状肿瘤 疗效 

分 类 号：R737.9[医药卫生—肿瘤]