The dual antimicrobial and immunomodulatory roles of host defense peptides and their applications in animal production  

作　　者：Di Wu Linglong Fu Weizhang Wen Na Dong 

机构地区：[1]State Key Laboratory of Animal Nutrition,College of Animal Science and Technology,China Agricultural University,Beijing 100193,China

出　　处：《Journal of Animal Science and Biotechnology》2023年第2期501-514,共14页畜牧与生物技术杂志（英文版）

基　　金：funded by NSFC grand(32172754).

摘　　要：Host defense peptides(HDPs)are small molecules with broad-spectrum antimicrobial activities against infectious bacteria,viruses,and fungi.Increasing evidence suggests that HDPs can also indirectly protect hosts by modulating their immune responses.Due to these dual roles,HDPs have been considered one of the most promising antibiotic substitutes to improve growth performance,intestinal health,and immunity in farm animals.This review describes the antimicrobial and immunomodulatory roles of host defense peptides and their recent applications in animal production.

关 键 词：Antimicrobials Host defense peptides IMMUNOMODULATION POULTRY RUMINANTS SWINE 

分 类 号：S816[农业科学—饲料科学]