3 T MRI三维T2加权快速梯度回波序列显示胎儿脊柱解剖及椎体畸形的评价  

Evaluation of fetal spinal anatomy and vertebral deformity with 3 T magnetic resonance three-dimensional T2-weighted fast field echo sequence

作　　者：何双 雷强 王芳 赵小丽 王志刚 赖华 文曦琳 HE Shuang;LEI Qiang;WANG Fang;ZHAO Xiaoli;WANG Zhigang;LAI Hua;WEN Xilin(Department of Radiology,Chengdu Women's and Children's Central Hospital,School of Medicine,University of Electronic Science and Technology of China,Chengdu 611731,China)

机构地区：[1]电子科技大学医学院附属妇女儿童医院·成都市妇女儿童中心医院放射科,成都611731

出　　处：《磁共振成像》2023年第3期111-116,共6页Chinese Journal of Magnetic Resonance Imaging

摘　　要：目的分析3 T MRI三维T2加权快速梯度回波(three-dimensional T2-weighted fast field echo,3D-T2*-FFE)序列显示胎儿脊柱解剖及椎体畸形的价值。材料与方法本研究纳入46例产前超声提示胎儿椎体异常或脊柱部分显示不清的中晚期孕妇,所有胎儿均行脊柱MRI检查,扫描序列包括:3D-T2*-FFE、二维单次激发快速自旋回波(two-dimensional single shot fast spin echo,2D SSH TSE)和二维平衡式自由稳态进动(two-dimensional balance turbo fast field echo,2D BTFE)。由两名诊断医师对三个序列获得的脊柱各节段图像质量进行评分,采用非参数检验之Friedman检验比较各序列图像之间评分的差异。对所有病例勾画感兴趣区(region of interest,ROI),并分别计算三个序列颈、胸、腰骶段相应的椎体与椎间盘信号差值比,以评价图像对比度,通过单因素方差分析比较三个序列各节段信号差值比的差异是否有统计学意义。结果与2D SSH TSE和2D BTFE序列相比3D-T2*-FFE可以获得更好的胎儿颈椎图像,2D BTFE与3D-T2*-FFE序列在胎儿胸椎及腰骶椎的图像质量均优于2D SSH TSE序列;3D-T2*-FFE和2D BTFE序列的信号差值比高于2D SSH TSE序列,且差异有统计学意义(P<0.05);胎儿胸椎和腰椎在各序列的信号差值比差异无统计学意义(P>0.05)。结论3D-T2*-FFE序列对胎儿椎体成像效果较好,能显示更多脊柱解剖细节,其不受胎儿体位影响,且扫描时间较短,临床MRI扫描时可将其作为胎儿脊柱成像的重要补充序列。Objective:To analyze the value of three-dimensional T2-weighted fast field echo(3D-T2*-FFE)in fetal spinal anatomy and vertebral deformity.Materials and Methods:Fourty-six middle and late pregnant women,whose prenatal ultrasound showed abnormal fetal vertebral bodies or unclear spine parts,were consecutively enrolled.All fetuses underwent corresponding spinal MRI examination on a 3 T MR with a 16-channel body matrix coil.The scanning MR sequences included 3D-T2*-FFE,two-dimensional single shot fast spin echo(2D SSH TSE)and two-dimensional balance turbo fast field echo(2D BTFE),region of interest(ROI)was carefully delineated for all cases to calculate the signal difference ratio of the corresponding vertebral bodies and intervertebral discs in the cervical,thoracic and lumbar segments with the three sequences respectively to evaluate image contrast.Results:Compared with 2D SSH TSE sequence and 2D BTFE sequence,3D-T2*-FFE sequence could obtain better image quality of fetal cervical vertebra.The image quality of 2D BTFE and 3D-T2*-FFE sequence was superior to that of 2D SSH TSE sequence in fetal thoracic vertebra and lumbosacral vertebra.The signal difference ratio values of 3D-T2*-FFE and 2D BTFE sequences were higher than those of 2D SSH TSE sequences,and the difference was statistically significant(P<0.05);The signal difference ratio values of thoracic vertebra and lumbar vertebra showed no significant difference in each sequence(P>0.05).Conclusions:3D-T2*-FFE sequences have better imaging effects on fetal vertebra under 3 T MRI,but 3D-T2*-FFE sequences can display more anatomical details of the spine.It is not affected by fetal position,and the scanning time is short,so it can be used as an important complementary sequence in clinical MRI of fetal spine.

关 键 词：产前诊断 胎儿脊柱 椎体畸形 磁共振成像 三维成像 T2加权快速梯度回波序列 

分 类 号：R445.2[医药卫生—影像医学与核医学] R714.53[医药卫生—诊断学]