外阴富于细胞性平滑肌瘤一例  

A Case Report of Cellular Vulvar Leiomyoma

作　　者：曾宇华 区晓榆 陈燕芬 谢琳玲 曾蕾[2] 卢如玲[2] ZENG Yu-hua;OU Xiao-yu;CHEN Yan-fen;XIE Lin-ling;ZENG Lei;LU Ru-ling(The First Clinical Medical College of Guangzhou University of Chinese Medicine,Guangzhou 510405,China;Department of Gynecology,The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China)

机构地区：[1]广州中医药大学第一临床医学院,510405 [2]广州中医药大学第一附属医院妇科

出　　处：《国际生殖健康／计划生育杂志》2023年第2期119-122,共4页Journal of International Reproductive Health/Family Planning

摘　　要：富于细胞性平滑肌瘤是一种少见的好发于子宫的交界性肿瘤,而发于外阴的富于细胞性平滑肌瘤在临床上更为罕见,位于前庭大腺的平滑肌瘤发病位置、临床表现与前庭大腺囊肿极为相似,因此临床上常易误诊为前庭大腺囊肿。病理学检查是明确诊断的主要方法,与普通平滑肌瘤相比,富于细胞性平滑肌瘤镜下可见编织状排列现象,细胞内可见丰富细胞质,而在细胞大小与形态上无明显差异。广州中医药大学第一附属医院收治1例外阴富于细胞性平滑肌瘤患者,结合患者病史、症状及体征在初诊时考虑前庭大腺囊肿,经手术切除病灶后送病理组织学检查及免疫组织化学检查,诊断为外阴富于细胞性平滑肌瘤。磁共振成像及彩色超声检查可帮助临床医师进行鉴别诊断,但其诊断多需通过手术切除后行病理检查。Cellular leiomyoma is a rare borderline tumor that occurs in the uterus,while cellular leiomyoma that occur in the vulva(cellular vulva leiomyoma)is more rare in the clinic.The location and clinical manifestations of leiomyomas located in the vestibular glands are very similar to those of Bartholin′s gland cysts,so these leiomyomas are often misdiagnosed as Bartholin′s gland cysts in clinical practice.Pathological examination is the main method for definite diagnosis.Compared with ordinary leiomyoma,cellular leiomyomas in histopathologic examination show the braided arrangement phenomenon and abundant cytoplasm.However,there is no significant difference in the cell size and morphology.Recently,a patient with a cellular vulvar leiomyoma was diagnosed and treated in the First Affiliated Hospital of Guangzhou University of Chinese Medicine.The patient was first diagnosed as the Bartholin′s gland cyst according to the history,symptoms and signs.The"cyst"was surgically excised,and for the histological examination and immunohistochemical examination confirmed the diagnosis of a cellular vulvar leiomyoma.MRI and colour ultrasound may help the clinician to make a differential diagnosis,while the definite diagnosis mostly requires pathological examination.

关 键 词：外阴肿瘤 平滑肌瘤 前庭大腺 囊肿 诊断 鉴别 免疫组织化学 

分 类 号：R737.33[医药卫生—肿瘤]