肝脏疾病患者临床生化常规及凝血酶原时间检查的结果探究  

Clinical Biochemical Routine and Prothrombin Time Test of Patients with Liver Disease

作　　者：王建华 余笑笑 朱凯敏 WANG Jianhua;YU Xiaoxiao;ZHU Kaimin(Department of Clinical Laboratory,Rugao Branch Affiliated Hospital of Nantong University(Rugao Bo'ai Hospital),Rugao,Jiangsu Province,226500 China)

机构地区：[1]南通大学附属医院如皋分院(如皋博爱医院)检验科,江苏如皋226500

出　　处：《系统医学》2022年第24期80-83,共4页Systems Medicine

摘　　要：目的探讨临床常规生化指标以及凝血酶在肝脏疾病中的意义。方法选取2020年1月—2022年3月南通大学附属医院如皋分院(如皋博爱医院)接收的120例肝脏疾病患者作为观察组,选取同期在本院进行健康体检人员120名作为对照组,对比两组血生化指标和凝血酶原时间,同时对比各种肝脏疾病患者的凝血酶原时间和血生化指标。结果观察组PT(13.83±6.24)s、TBA(60.29±1.02)μmol/L、ALT(69.22±3.23)U/L、GGT(40.56±2.75)U/L均高于对照组,CHE(4481.39±8.20)U/L低于对照组,差异有统计学意义(t=6.703、6.393、8.504、9.284、5.345,P<0.05)。急性肝炎、慢性肝炎、肝硬化、肝癌患者的TBA、CHE、GGT、ALT和PT比较,差异有统计学意义(P<0.05);急性肝炎患者CHE高于其他疾病患者,肝癌患者PT、TBA、ALT、GGT水平均高于其他疾病患者,差异有统计学意义(P<0.05)。结论血生化指标以及凝血酶原时间检测,可以了解肝脏疾病患者病情,为了有效鉴别各类肝脏疾病,判断肝功能的受损情况,有必要检测血生化指标以及凝血酶原时间。Objective To explore the clinical routine biochemical indexes and the significance of thrombin in liver diseases.Methods A total of 120 patients with liver disease admitted to Rugao Branch Affiliated Hospital of Nantong University Rugao Bo'ai Hospital,from January 2020 to March 2022 were selected as the observation group,and 120 people who underwent physical examination in the hospital during the same period were selected as the control group.The blood biochemical indexes and prothrombin time test results of the two groups were compared,and the prothrombin time and blood biochemical indexes of patients with various liver diseases were compared.Results The PT(13.83±6.24)s,TBA(60.29±1.02)μmol/L,ALT(69.22±3.23)U/L,GGT(40.56±2.75)U/L in the observation group were higher than those in the control group,and CHE(4481.39±8.20)U/L was lower than thah in the control group,the difference was statistically significant(t=6.703,6.393,8.504,9.284,5.345,P<0.05).Comparison of TBA,CHE,GGT,ALT,and PT in patients with acute hepatitis,chronic hepatitis,liver cirrhosis,and liver cancer,the difference was statistically significant(P<0.05).The levels of CHE in patients with acute hepatitis was higher than that in patients with other diseases,the levels of PT,TBA,ALT and GGT in HCC patients were higher than those in patients with other diseases,the difference was statistically significant difference(P<0.05).Conclusion The detection of blood biochemical indexes and prothrombin time can understand the condition of patients with liver diseases.In order to effectively identify various liver diseases and judge the damage of liver function,it is necessary to detect blood biochemical indexes and prothrombin time.

关 键 词：肝脏疾病 生化常规 凝血酶原 检测 

分 类 号：R446[医药卫生—诊断学]