免疫组化在肿瘤病理诊断中的应用  

Application of immunohistochemistry in pathological diagnosis of tumor

作　　者：慈红非 吴礼高[1] CI Hong-fei;WU Li-gao(Pathology Teaching and Research Office,Benghu Medical College,Department of Pathology,First Affiliated Hospital of Bengbu Medical College,Bengbu Anhui Province 233000,China)

机构地区：[1]蚌埠医学院病理学教研室,蚌埠医学院第一附属医院病理科,安徽蚌埠233000

出　　处：《中国城乡企业卫生》2023年第2期111-113,共3页Chinese Journal of Urban and Rural Enterprise Hygiene

摘　　要：目的 探讨免疫组化在肿瘤病理诊断中的应用效果,为临床提供参考依据。方法 选取2020年2月—2021年8月蚌埠医学院第一附属医院收治的64例肿瘤患者,随机分为对照组和观察组各32例,对照组采用常规诊断技术,观察组采用免疫组化诊断技术。分析两组阳性检出状况、生理问题评分、心理顾虑评分、信任感评分及诊断满意率。结果观察组诊断阳性率为84.38%,高于对照组的62.50%,差异有统计学意义(χ^(2)=7.849,P<0.05)。观察组生理问题、心理顾虑、信任感评分分别为(90.28±2.96)分、(90.34±3.15)分、(92.47±2.51)分,高于对照组的(83.15±3.15)分、(84.26±2.57)分、(83.15±3.23)分,差异均有统计学意义(P<0.05)。观察组诊断总满意率为93.75%,高于对照组的78.13%,差异有统计学意义(χ^(2)=5.494,P<0.05)。结论 肿瘤病理诊断过程中,与常规穿刺活检技术比较,免疫组化诊断应用价值更高,不仅可以提高肿瘤疾病阳性检出率,而且有助于患者检查舒适度和信任感等提高,使其可以主动接受诊治,此外,该方法能够提升诊断满意率,改善紧张的护患关系,值得临床应用推广。Objective To investigate the application effect of immunohistochemistry in the pathological diagnosis of tumors,in order to provide reference for clinical practice. Methods A total of 64 tumor patients in First Affiliated Hospital of Bengbu Medical College from February 2020 to August 2021 were selected,and randomly divided into control group and observation group,with 32 cases in each group. The control group received routine diagnostic techniques and the observation group received immunohistochemical diagnostic techniques,and the positive detection status,physiological problems score,psychological concerns score,trust score and diagnostic satisfaction rate were analyzed between the two group. Results The positive rate was 84.38% in the observation group,which was higher than 62.50%in the control group,and the differences were statistically significant (χ^(2)=7.849,P<0.05). In terms of the score of physical problems,psychological concerns and trust,the scores of the observation group were(90.28±2.96),(90.34±3.15)and(92.47±2.51)ponts,respectively,which were higher than(83.15±3.15),(84.26±2.57)and(83.15±3.23) points of the control group,and the differences were statistically significant(P<0.05). The total satisfaction rate of diagnosis in the observation group was 93.75%,which was higher than 78.13% in the control group,and the difference was statistically significant (χ^(2)=5.494,P <0.05). Conclusion In the process of tumor pathological diagnosis,compared with the conventional puncture biopsy technology,immunohistochemical diagnosis had a higher application value,which could not only improve the positive detection rate of tumor diseases,but also help patients to improve their comfort and sense of trust,so that they could take the initiative to receive diagnosis and treatment. In addition,this method could improve the diagnosis satisfaction rate,improve the tense nurse-patient relationship,and was worthy of clinical adoption and promotion.

关 键 词：肿瘤 病理诊断 免疫组化 

分 类 号：R36[医药卫生—病理学]