iRoot SP配合单尖法根管充填治疗牙体牙髓病的效果及对牙周状态和龈沟液炎性因子水平的影响  

Effect of iRoot SP Combined with Single-point Root Canal Filling in the Treatment of Dental Pulp Disease and Its Impact on Periodontal Statusand the Level of Inflammatory Factors in Gingival Crevicular Fluid

作　　者：张帆[1] 陈新钊 蒙萌 ZHANG Fan;CHEN Xinzhao;MENG Meng(Department of Stomatology,Northwestern Polytechnical University Hospital,Xi'an 710072,China;Department of Stomatology,the Second Affiliated Hospital of Air Force Medical University,Xi'an 710038,China;State Key Laboratory of Military Stomatology,National Clinical Research Centre for Oral Diseases,Shaanxi Key Laboratory of Stomatology,Department of Prosthodontics,School of Stomatology,the Fourth Military Medical University,Xi'an 710032,China)

机构地区：[1]西北工业大学医院口腔科,西安710072 [2]空军军医大学第二附属医院唐都医院口腔科,西安710038 [3]军事口腔医学国家重点实验室,口腔疾病国家临床医学研究中心,陕西省口腔医学重点实验室,空军军医大学口腔医院口腔修复科,西安710032

出　　处：《临床误诊误治》2023年第3期105-108,122,共5页Clinical Misdiagnosis & Mistherapy

基　　金：陕西省卫生健康科研基金项目(2021B003)。

摘　　要：目的 探讨iRoot SP配合单尖法根管充填治疗牙体牙髓病的效果及对牙周状态和龈沟液炎性因子水平的影响。方法 选取2020年1月—2022年1月收治的牙体牙髓病82例,按治疗方法分为观察组和对照组各41例,观察组应用iRoot SP配合单尖法治疗,对照组应用iRoot SP配合冷测压法治疗。比较2组临床疗效、充填情况、牙周状态、龈沟液炎性因子水平及疼痛情况。结果 治疗后,观察组临床总有效率和恰填率高于对照组(P<0.05)。观察组治疗后牙周探诊深度、探诊出血指数、牙齿松动度、菌斑指数、临床附着水平及超敏C反应蛋白、肿瘤坏死因子-α、白细胞介素-1β均低于对照组(P<0.05,P<0.01)。治疗后,观察组疼痛总发生率低于对照组(P<0.05)。结论 iRoot SP配合单尖法根管充填能够提高牙体牙髓病的临床疗效,改善患者充填情况以及牙周状态,降低龈沟液炎性因子水平及减轻患者疼痛。Objective To investigate the effect of iRoot SP combined with single-point root canal filling in the treatment of dental pulp disease and its effect on periodontal status and inflammatory factors in gingival crevicular fluid.Methods A total of 82 patients with dental pulp disease treated from January 2020 to January 2022 were selected and divided into observation group(n=41)and control group(n=41)according to treatment methods.The observation group was treated with iRoot SP combined with single-point method,and the control group was treated with iRoot SP combined with cold manometry method.The clinical efficacy,filling condition,periodontal status,levels of inflammatory factors in gingival crevicular fluid and pain of the two groups were compared.Results After treatment,the total effective rate and filling rate of the observation group were higher than those of the control group(P<0.05).After treatment,the periodontal probing depth,probing bleeding index,tooth looseness index,plaque index,clinical attachment level,hypersensitive C reactive protein,tumor necrosis factor-αand interleukin-1βin observation group were lower than those in control group(P<0.05,P<0.01).After treatment,the total incidence of pain in the observation group was lower than that in the control group(P<0.05).Conclusion iRoot SP combined with single-point root canal filling can improve the clinical efficacy of endodontic pulp disease,improve the filling condition and periodontal status of patients,reduce the level of inflammatory factors in gingival crevicular fluid and relieve the pain of patients.

关 键 词：牙体牙髓病 iRoot SP 单尖法 根管充填 牙周探诊深度 菌斑指数 龈沟液 超敏C反应蛋白 肿瘤坏死因子-α 

分 类 号：R781[医药卫生—口腔医学]