Quite amusing stem cells:Muse cells  

作　　者：Molly Monsour Cesar V.Borlongan 

机构地区：[1]University of South Florida Morsani College of Medicine,Tampa,FL,USA [2]Department of Neurosurgery and Brain Repair,University of South Florida,Morsani College of Medicine,Tampa,FL,USA

出　　处：《Neural Regeneration Research》2023年第11期2377-2378,共2页中国神经再生研究（英文版）

基　　金：CVB was funded by the National Institutes of Health NIH R01NS090962,NIH R01NS102395,NIH R21 NS1095 75;CVB was funded and received royalties and stock options from Astellas,Asterias,Sanbio,Athersys,KMPHC;International Stem Cell Corporation and has also received consultant compensation from Chiesi Farmaceutici。

摘　　要：Stem cells may be the future of therapeutics for stroke due to their regenerative and immunomodulatory capabilities.Major barriers faced when employing stem cells,however,include faulty migration,low cell survival,and diminished proliferation.M ultilineage-differentiating stress ensuring (Muse) cells,a subset of mesenchymal stem cells,overcome these barriers.Muse cells aid in neuroregeneration,have immense regenerative potential,and are pluripotent,non-tumorigenic,and immunomodulatory.In stroke specifically,these cells may restore an a nti-inflammatory environment,regenerate damaged neurons,and integrate into the neuronal architecture.In fact,Muse cells may be aptly designed to ameliorate neurovascular unit damage following stroke and observed in other neuroinflammatory disorders.

关 键 词：MODULATOR OVERCOME INTEGRATE 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]