载Ag/Cu纳米粒子多孔聚丙烯腈复合纤维膜的制备及其抑菌性  

Preparation and antibacterial properties of porous polyacrylonitrile composite fiber membrane loaded with silver/copper nanoparticles

作　　者：徐鹏[1] 汪杨 王莎莎 戴伟 陈难难 李群 XU Peng;WANG Yang;WANG Shasha;DAI Wei;CHEN Nannan;LI Qun(College of Chemical Engineering,Nanjing Forestry University,Nanjing 210037,China)

机构地区：[1]南京林业大学化学工程学院,南京210037

出　　处：《复合材料学报》2023年第2期836-843,共8页Acta Materiae Compositae Sinica

基　　金：江苏省自然科学基金(BK20130969)。

摘　　要：金属纳米粒子因其独特的物理化学性能,在催化、抑菌、水污染处理和生物医学等领域表现出巨大的应用前景。但是金属纳米粒子在制备和使用过程中容易发生团聚而影响其性能。因此,提高金属纳米粒子的稳定性,对提升其应用性能具有重大意义。本文在以聚丙烯腈(PAN)为基体,聚乙烯吡咯烷酮(PVP)为致孔剂,基于静电纺丝技术制得多孔聚丙烯腈纳米纤维(PPAN NFs)的基础上,通过浸渍沉积法分别制备出负载银纳米粒子(Ag NPs)复合纳米纤维(Ag-PPAN NFs)和负载铜纳米粒子(Cu NPs)复合纳米纤维(Cu-PPAN NFs)。在利用FESEM、EDS、XRD等方法对制备纤维膜的形貌和结构进行表征的基础上,通过抑菌圈法和FESEM观察经复合纳米纤维处理前后的细菌形貌来研究Ag-PPAN NFs和Cu-PPAN NFs对大肠杆菌、金黄色葡萄球菌和白色念球菌的抑菌性能。研究结果发现:PPAN NFs可有效解决Ag NPs和Cu NPs在制备和使用过程中易于聚集的问题,制得的复合纳米纤维对大肠杆菌、金黄色葡萄球菌和白色念球菌具有一定的抗菌活性,可成为一种新型的抗菌纤维材料。Metal nanoparticles show great application on prospect in catalysis,bacteriostasis,water pollution treatment and biomedicine,because of their unique physical and chemical properties.Metal nanoparticles tend to agglomerate in the processes of preparation and use.Therefore,improving the stability of nanoparticles is of great significance to improve their application performance.In this study,porous polyacrylonitrile nanofibers(PPAN NFs)were prepared by electrostatic spinning using polyacrylonitrile(PAN)as substrate and polyvinylpyrrolidone(PVP)as the pore-making agent.On this basis,Ag-PPAN NFs and Cu-PPAN NFs were prepared by in-situ loading of silver and copper nanoparticles on the surface of PPAN NFs by impregnation deposition.The morphologies and structures of the prepared nanofibers were characterized by FESEM,EDS and XRD,and the antibacterial properties of Ag-PPAN NFs and Cu-PPAN NFs against E.coli,S.aureus and C.albicans were studied by bacteriostatic zone method and FESEM observation.The results show that PPAN NFs provide a rich mesoporous structure for loading of Ag NPs and Cu NPs and inhibited the aggregation of nanoparticles.The prepared Ag-PPAN NFs and Cu-PPAN NFs show good antibacterial activities against E.coli,S.aureus and C.albicans,and which could be used as a new kind of antibacterial fiber material.

关 键 词：银纳米粒子 铜纳米粒子 多孔 纳米纤维 静电纺丝 抑菌 

分 类 号：TB331[一般工业技术—材料科学与工程]