溃疡性结肠炎患者生存质量的相关影响因素分析  

A observational study on the influencing factors of quality of life scale in ulcerative colitis

作　　者：刘小娟 朱磊[1] 沈照峰 王志斌[2] 苏晓兰[3] 刘亚军[1] 张露[1] 孙心 郑凯[1] 连紫宇 沈洪[1] LIU Xiaojuan;ZHU Lei;SHEN Zhaofeng;WANG Zhibin;SU Xiaolan;LIU Yajun;ZHANG Lu;SUN Xin;ZHENG Kai;LIAN Ziyu;SHEN Hong(Department of Gastroenterology,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing,210029,China;Department of Gastroenterology,Dongfang Hospital,Beijing University of Traditional Cinese Medicine;Department of Spleen and Stomach Diseases,Wangjing Hospital,China Academy of Chinese Medical Sciences;Department of Acupuncture and Physiotherapy,Heping Hospital Affiliated to Changzhi Medical College)

机构地区：[1]南京中医药大学附属医院消化科,南京210029 [2]北京中医药大学东方医院消化科 [3]中国中医科学院望京医院脾胃病科 [4]长治医学院附属和平医院针灸理疗科

出　　处：《中国中西医结合消化杂志》2023年第3期179-182,187,共5页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：国家重点研发计划中医药现代化研究专项(No:2017YFC1700104);江苏省重点研发计划(No:BE2019769)。

摘　　要：目的:探讨影响溃疡性结肠炎患者生存质量的相关因素,以期为改善患者的生存质量提供指导。方法:选取2019年8月—2022年1月就诊于南京中医药大学附属医院、北京中医药大学东方医院、中国中医科学院望京医院的354例UC患者的调查信息,构建数据库,基于SPSS 26.0进行频数、线性回归方程等统计分析。观察不同因素对患者健康调查简表(SF-36量表)得分的影响。结果:BMI影响生理功能(P=0.003)、躯体职能(P=0.015)、总体健康(P=0.024)、精力(P=0.001)和精神健康(P=0.033)维度得分;性别因素影响躯体疼痛(P=0.007)、总体健康(P=0.024)和精神健康(P=0.005)维度得分;Mayo积分影响生理功能(P=0.002)、躯体职能(P=0.005)、躯体疼痛(P=0.029)和总体健康(P=0.013)维度得分;肠外表现影响生理功能(P=0.015)和躯体疼痛(P<0.001)维度得分;病变范围影响躯体疼痛(P=0.047)维度得分;临床分期影响精神健康(P=0.015)维度得分。BMI、病变范围、Mayo积分影响总分的高低。结论:性别、BMI、Mayo积分、疾病分期、病变部位等因素对溃疡性结肠炎患者的生存质量量表得分有影响。Objective:Investigate the related factors of quality of life in patients with ulcerative colitis,and provide guidance for improving the quality of life of patients.Methods:A total of 354patients with ulcerative colitis who were admitted to the Affiliated Hospital of Nanjing University of Chinese Medicine,Dongfang Hospital of Beijing University of Chinese Medicine and Wangjing Hospital of China Academy of Chinese Medical Sciences from August 2019to January 2022were selected to construct the database.Statistical analysis of frequency and linear regression equation was conducted based on SPSS 26.0.Results:Observe the effects of different factors on the score of the SF-36scale,and the results showed that BMI affected the scores of PF(P=0.003),RP(P=0.015),GH(P=0.024),VT(P=0.001)and MH(P=0.033).Gender factors affected the scores of BP(P=0.007),GH(P=0.024)and MH(P=0.005).Mayo index affects the scores of PF(P=0.002),RP(P=0.005),BP(P=0.029),and GH(P=0.013).Extraintestinal manifestations affected the scores of PF(P=0.015)and BP(P<0.001).The range of lesions affected the score of BP(P=0.047).Clinical stage affected mental health score(P=0.015).BMI,lesion range and Mayo index affected the total score.Conclusion:Factors such as gender,BMI,Mayo score,disease stage and lesion range had influence on QOL scale score of patients with ulcerative colitis.

关 键 词：溃疡性结肠炎 生存质量 调查健康简表 SF-36量表 影响因素 

分 类 号：R574.62[医药卫生—消化系统]