新型冠状病毒感染相关的眼底病变  

COVID-19 related fundus disease

作　　者：朱瑞琳[1] 杨柳[1] Zhu Ruilin;Yang Liu(Department of Ophthalmology,Peking University First Hospital,Beijing 100034,China)

机构地区：[1]北京大学第一医院眼科,北京100034

出　　处：《中华眼底病杂志》2023年第3期254-259,共6页Chinese Journal of Ocular Fundus Diseases

基　　金：国家自然科学基金(82171059)。

摘　　要：新型冠状病毒感染(COVID-19)相关眼底病变多与血管阻塞或炎症性改变相关,受到影响的血管既有视网膜大血管,也有微血管,炎症改变多为自身免疫性病变,在临床上出现不同的眼底改变,对视功能的影响轻重不一。这些病变的发生机制,考虑与严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)直接损伤、SARS-CoV-2导致的凝血异常或炎症反应相关。通过对COVID-19相关眼底病变的认识,有助于进一步了解COVID-19的病理生理机制,开展深入研究,以期对COVID-19的发生和全面影响有更深入的理解和完整认识,强调对疾病早期防控的重要性,注意对COVID-19导致的眼底损害及早进行干预和积极治疗。COVID-19 associated fundus lesions are mostly vascular occlusion or inflammatory changes.The affected vessels include both retinal macrovessels and microvessels,and the inflammatory changes are mainly autoimmune lesions.Clinically,the different lesions present as various fundus diseases,with varying degrees of impact on visual function.The mechanism of these lesions is considered to be related to direct injury of SARS-CoV-2,abnormal coagulation or inflammatory response caused by SARS-CoV-2.Awareness of fundus lesions associated to COVID-19 is helpful to figure out the pathophysiological mechanism of COVID-19 and promote in-depth studies for a deeper and complete understanding of the occurrence and full impact of COVID-19,emphasizing the importance of early prevention and control of the disease,and highlighting the significance of early intervention of the fundus diseases caused by COVID-19.

关 键 词：新型冠状病毒感染 严重急性呼吸道综合征冠状病毒2型 视网膜 视神经 视网膜病变 综述 

分 类 号：R774.1[医药卫生—眼科]