Copper-Initiated Radical Dearomative 2,5-Alkylarylation of Furans via Trihalomethylation/Spirocyclization Cascade  

作　　者：Wenkun Luo Kai Jiang Biaolin Yin 

机构地区：[1]Key Laboratory of Functional Molecular Engineering of Guangdong Province,School of Chemistry and Chemical Engineering,South China University of Technology,Guangzhou,Guangdong,510640 China [2]Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation,School of Chemistry and Engineering,Changsha University of Science and Technology,Changsha,Hunan,410114 China

出　　处：《Chinese Journal of Chemistry》2022年第24期2893-2899,共7页中国化学（英文版）

基　　金：supported by the National Natural Science Foundation of China(21871094);the Guangxi Key Laboratory of Zhuang and Yao Ethnic Medicine[(2014)No.32];We also thank the support of the Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation(No.2021CL04).

摘　　要：Here is an operable and rare strategy for copper-initiated radical dearomative 2,5-alkylarylation of furan. By means of this strategy, we realized the dearomatization of furans to construct spirooxindoles with good yield in one-step via trihalomethylation/spirocyclization cascade progress.

关 键 词：COPPER Radical reactions DEAROMATIZATION Trihalomethylation Spiro compounds 

分 类 号：O62[理学—有机化学]