supported by the National Natural Science Foundation of China(22125108 and 22121001 for Ye LW,22122109 and 22271253 for Hong X);the National Key R&D Program of China(2022YFA1504301,Hong X);the Zhejiang Provincial Natural Science Foundation of China(LDQ23B020002,Hong X);the Starry Night Science Fund of Zhejiang University Shanghai Institute for Advanced Study(SNZJU-SIAS-006,Hong X);the Beijing National Laboratory for Molecular Sciences(BNLMS202102,Hong X);the CAS Youth Interdisciplinary Team(JCTD-2021-11,Hong X);the Fundamental Research Funds for the Central Universities(226-2022-00140,226-2022-00224,and 226-2023-00115,Hong X);the State Key Laboratory of Physical Chemistry of Solid Surfaces(202210,Hong X);the Leading Innovation Team grant from the Department of Science and Technology of Zhejiang Province(2022R01005,Hong X);the Natural Science Foundation of Jiangsu Province(BK20211059);National Found for Fostering Talents of Basic Science(NFFTBS,J1310024).
Herein,we disclose a highly regio-/chemoselective tandem asymmetric dearomatized halofunctionalization reaction of phenoltethered ynamides with diverse electrophilic halogenation sources in a catalyst-free manner for ...
supported by the Natural Science Foundation of Jilin Province(20210101134JC);the National Natural Science Foundation of China(22171042,21831002,22193012);the Fundamental Research Funds for the Central Universities.
Alicyclic nitrogen heterocycles,such as enantioenriched polycyclic fused[1,2-a]indoline derivatives,are widespread in natural products,agrochemicals and pharmaceutical agents.Existing methods predominantly rely on the...
the Qingdao Marine Science and Technology Center(No.2022QNLM030003-2);the Fundamental Research Funds for the Central Universities,Taishan Scholar Program of Shandong Province(No.tsqn202103152);National Natural Science Foundation of China(No.22171251) for financial support。
The first total synthesis of(+)-taberdicatine B and(+)-tabernabovine B has been accomplished in 10steps with 26.9% overall yield and 15 steps with 7.3% overall yield,respectively.The prominent features of this efficie...
supported by the Ministry of Science and Technology of China(grant no.2021YFF0701700);the National Natural Science Foundation of China(grant nos.22122104,22193012,and 21933004);the CAS Project for Young Scientists in Basic Research(grant nos.YSBR-052 and YSBR-095);the Strategic Priority Research Program of the Chinese Academy of Sciences(grant no.XDB0590000).
Catalytic asymmetric dearomatization(CADA)of phenols has emerged as a powerful strategy for constructing stereochemically complicated architectures from planar aromatic feedstocks.However,the development of novel cata...
supported by the National Natural Science Foundation of China(22188101);Sichuan Science and Technology Program(2021YJ0561)。
An efficient catalytic asymmetric dearomatizing amination of 2-naphthols and phenols catalyzed by N,N′-dioxide-copper(I)complex as a chiral catalyst was presented.A variety of optically activeβ-naphthalenone compoun...
the National Natural Science Foundation of China(grant no.22271251);the Fundamental Research Funds for the Central Universities(grant nos.226-2023-00016,226-2023-00115,and 226-2022-00224).
In sharp contrast to the well researched and well developed aminocarbonylation of alkenes,the dearomative carbamoylation of abundant areneπ-systems has scarcely been studied despite its great potential to enrich the ...
the Natural Science Foundation of Zhejiang Province(LY22B020001);the Zhejiang Public Welfare Public Research Program(LGC22B010001);the National Natural Science Foundation of China(32201238)is greatly acknowledged.
Functionalized free radical addition/cyclization reactions represent an efficient way for introducing new functionality or coupling fragments to molecules.Ynones are good regional selectivity radical acceptors in orga...
the National Natural Science Foundation of China(Nos.22171154 and 21801144);the Youth Innovative Talents Recruitment and Cultivation Program of Shandong Higher Education,the Natural Science Foundation of Shandong Province(Nos.ZR2020QB114 and ZR2020QB008);Jinan Science&Technology Bureau(No.2021GXRC080);supported by the Foundation(No.ZZ20190312)of State Key Laboratory of Biobased Material and Green Papermaking,Qilu University of Technology(Shandong Academy of Sciences);the Program for Scientific Research Innovation Team in Colleges and Universities of Shandong Province,the Open Fund of the Department of Chemistry,Qingdao University of Science and Technology(No.QUSTHX202010);Science and Technology Innovation Development Plan of Yantai(No.2020MSGY114);Yantai“Double Hundred Plan”.
We demonstrated herein an electrochemical dearomatizative alkylation of Katritzky salts,wherein Katritzky salts were harnessed as both radical acceptors and donors.A wide range of privileged dihydropyridine scaffolds ...
supported by the National Natural Science Foundation of China(No.22171046);the Hundred-Talent Project of Fujian(No.50021113).
The development of efficient and sustainable methods to obtain spirocyclic compounds is of significance as these structures are widely found in pharmaceuticals and agrochemicals.Herein,we disclose an electrochemical d...
the generous financial support from Natural Science Foundation of Henan Province (No.222300420084);application research plan of Key Scientific Research Projects in Colleges and Universities of Henan Province (No.22A150056);the Youth Innovation Team Program in Colleges and Universities of Shandong Province (No.2022KJ228);National Natural Science Foundation of China (No.22208302)。
Due to the high electrophilic nature of azo-dienophiles, azo-Diels–Alder proceeds rapidly even without the need of a catalyst and is therefore regarded as the “click reaction”. This spontaneity causes strong backgr...