Photocatalytic Site-Selective Cascade Radical Addition of Biaryl Ynones for the Construction of Spiro-and Fused Carbon Rings  

作　　者：Kairui Liu Chunhang Zhao Liji Gu Xiang Li Jiali Yan Siqi Lao Weiwei Huan Yan Zhang 

机构地区：[1]Key Laboratory of the Ministry of Education for Advanced Catalysis Materials,and Drug Discovery&Innovation Center,College of Chemistry and Materials Science,Zhejiang Normal University,Jinhua,Zhejiang,321004 China [2]Zhejiang Provincial Key Laboratory of Chemical Utilization of Forestry Biomass,College of Chemistry and Materials Engineering,Zhejiang A&F University,Hangzhou,Zhejiang,311300 China

出　　处：《Chinese Journal of Chemistry》2024年第14期1599-1605,共7页中国化学（英文版）

基　　金：the Natural Science Foundation of Zhejiang Province(LY22B020001);the Zhejiang Public Welfare Public Research Program(LGC22B010001);the National Natural Science Foundation of China(32201238)is greatly acknowledged.

摘　　要：Functionalized free radical addition/cyclization reactions represent an efficient way for introducing new functionality or coupling fragments to molecules.Ynones are good regional selectivity radical acceptors in organic synthesis,and many of bio-relevant cyclic compounds could be easily obtained by direct radical cyclization reaction.Here,we report a photocatalytic cascade radical addition of biaryl ynones,for the divergent synthesis of privileged carbon cycles.Additionally,further transformation of the multi-functional group product into a variety of other derivatives demonstrates the synthetic value of this developed method.

关 键 词：YNONES Photocatalysis Cascade cyclization Alkoxycarbonyl radical DEAROMATIZATION BIARYLS Regioselectivity Radical reactions 

分 类 号：O62[理学—有机化学]