急性斑蝥中毒致口腔黏膜病变及流产1例及文献复习  

Oral Mucosal Lesions and Abortion Caused by Acute Cantharidin Poisoning:a Case Report and Literature Review

作　　者：张志强 郭骏[2] 文才 雷博[1] 江蓉[1] 钟应权 ZHANG Zhi-qiang;GUO Jun;WEN Cai;LEI Bo;JIANG Rong;ZHONG Ying-quan(Department of Stomatology,Aba Prefecture People’s Hospital,Aba 624000,China;Department of Oral and Maxillofacial Surgery,Sichuan Provincial People’s Hospital,Chengdu 610072,China;Department of Implantology,Stomatological Hospital Affiliated to Southwest Medical University,Luzhou 646000,China)

机构地区：[1]阿坝州人民医院口腔科,四川阿坝624000 [2]四川省人民医院口腔颌面外科,成都610072 [3]西南医科大学附属口腔医院种植科,四川泸州646000

出　　处：《实用临床医学（江西）》2023年第1期55-58,共4页Practical Clinical Medicine

摘　　要：目的加深医护人员对急性斑蝥中毒的临床诊治的理解。方法回顾性分析1例孕早期急性斑蝥中毒患者的临床资料,分析其临床特点、检查及诊断方法、治疗策略、发病机制及预后转归,并进行文献复习。结果本例患者以口咽及消化系统黏膜病变损伤表现发病,实验室检查见感染、肝肾功能损伤及内环境代谢紊乱,经过早期多学科协作,对患者综合干预,行利尿解毒、保护黏膜及纠正机体内环境代谢紊乱,患者治疗预后良好,无继发及余留并发症。结论急性斑蝥中毒是一种罕见的中毒性疾病,应根据患者的具体情况进行个体化、对症治疗,安全地解毒后使用黏膜保护剂能有效减轻患者主观症状,联合多科诊疗用药可减少重要脏器及功能继发损害,提高其预后及治愈率。Objective To deepen medical staff’s understanding of clinical diagnosis and treatment of acute cantharidin poisoning.Methods The clinical data of a patient with acute cantharidin poisoning in early pregnancy were retrospectively analyzed.The clinical characteristics,examination and diagnosis methods,treatment strategies,pathogenesis,and prognosis were analyzed.In addition,the relevant literature was reviewed.Results This patient presented with oropharyngeal and digestive system mucosal lesions.Laboratory examinations showed infection,liver and kidney function damage,and metabolic disorders.After comprehensive multidisciplinary intervention with diuresis,detoxification,mucosal protection,and correction of metabolic disorders,the patient had a good prognosis and no secondary or residual complications.Conclusion Acute cantharidin poisoning is a rare toxic disease that should be treated individually and symptomatically according to the specific conditions of patients.The use of mucosal protective agents after safe detoxification can effectively alleviate the subjective symptoms.Multidisciplinary cooperative diagnosis and treatment can reduce secondary damage to important organs and functions,and improve the prognosis and cure rate.

关 键 词：斑蝥中毒 黏膜病变 口腔 

分 类 号：R781.66[医药卫生—口腔医学]