腹部CT增强扫描分析患者血流动力学对胃癌病理分级的术前预测价值分析  

Analysis on Preoperative Prediction Value of Enhanced Abdominal CT Scanning in Analyzing Patients'Hemodynamics for Pathological Grading of Gastric Cancer

作　　者：车睿贞 李琰 CHE Ruizhen;LI Yan(Department of Medical Imaging,the First Affiliated Hospital of He'nan University,Kaifeng 475001,China)

机构地区：[1]河南大学第一附属医院医学影像科,河南开封475001

出　　处：《临床医学工程》2023年第3期293-294,共2页Clinical Medicine & Engineering

基　　金：二〇二二年开封市科技发展计划“基于能谱CT的影像组学在术前预测胃癌病理分级中的价值研究”(项目编号:2207008)。

摘　　要：目的分析腹部CT增强扫描分析患者血流动力学对胃癌病理分级的术前预测价值。方法将80例胃癌患者根据病理分级结果分为低分化组与中高分化组。所有患者均行腹部CT增强扫描,记录血流动力学指标[血容量(BV)、血流量(BF)、表面通透性(PS)、平均通过时间(MTT)],绘制ROC曲线分析血流动力学指标对胃癌病理分级的术前预测价值。结果两组的BV、MTT比较无统计学差异(P>0.05);低分化组的BF、PS低于中高分化组(P<0.05)。ROC曲线分析结果显示,BF、PS对胃癌病理分级均具有显著的术前预测价值(AUC>0.7,P<0.05)。结论胃癌患者病理分级增加伴随BF与PS升高,临床应用腹部CT增强扫描检测BF、PS可评估其术前病理分级,为后续治疗方案的制定与改善提供参考。Objective To analyze the preoperative prediction value of enhanced abdominal CT scanning in analyzing patients'hemodynamics for pathological grading of gastric cancer.Methods 80 patients with gastric cancer were divided into low-differentiation group and medium-high-differentiation group according to the pathological grading results.All patients received enhanced abdominal CT scanning.The hemodynamic indicators[blood volume(BV),blood flow(BF),surface permeability(PS),mean passage time(MTT)]were recorded.ROC curve was drawn to analyze the preoperative prediction value of hemodynamic indicators in the pathological grading of gastric cancer.Results No statistical difference was found in the BV and MTT between the two groups(P>0.05).The BF and PS of the low-differentiation group were lower than those of the medium-high-differentiation group(P<0.05).ROC curve analysis showed that BF and PS had significant preoperative prediction value for pathological grading of gastric cancer(AUC>0.7,P<0.05).Conclusions The increase of pathological grading of gastric cancer patients is accompanied by the increase of BF and PS.The clinical application of abdominal enhanced CT scanning to detect the BF and PS can evaluate the preoperative pathological grading of patients,and provide reference for the formulation and improvement of follow-up treatment plans.

关 键 词：腹部CT增强扫描 血流动力学 胃癌 病理分级 

分 类 号：R735.2[医药卫生—肿瘤]