两例哒嗪羧基衍生物构筑的铜配合物  

Two Cu(Ⅱ) Complexes of Pyridazine Carboxylate Derivatives

作　　者：陈杨丹 王欣悦 李可心 高嘉豪 CHEN Yang-dan;WANG Xin-yue;LI Ke-xin;GAO Jia-hao(College of Chemical and Environment Science,Shaanxi University of Technology,Hanzhong,Shaanxi 723001,China)

机构地区：[1]陕西理工大学化学与环境科学学院,陕西汉中723001

出　　处：《浙江化工》2023年第3期17-22,共6页Zhejiang Chemical Industry

基　　金：大学生创新创业训练计划立项项目(SLGHX2022008)。

摘　　要：以1,3-二咪唑丙烷(1,3-BIP)、5-甲基-4-氧代-1-苯基-1,4-二氢哒嗪-3-羧酸(HPDC)和Cu(NO3)2·3H2O为原料,合成了两例配合物SNUT-1和SNUT-2。利用元素分析、红外光谱、X射线单晶衍射对配合物进行表征。结果表明,SNUT-1属于三斜晶系,P-1空间群,通过分子间氢键形成3D超分子结构;SNUT-2属于单斜晶体,P2(1)/c空间群,分子之间形成1D链并最终变为1D框架结构。抑菌测试结果表明,配合物SNUT-1对大肠杆菌和金黄色葡萄球菌均有较好的抑菌作用。Two complexes SNUT-1 and SNUT-2 were synthesized from 1,3-diimidazolepropane(1,3-BIP),5-methyl-4-oxy-1-phenyl-1,4-dihydropyrazine-3-carboxylic acid(HPDC)and Cu(NO3)2·3H2O.The complexes were characterized by elemental analysis,infrared spectroscopy and X-ray single crystal diffraction.The results show that SNUT-1 belongs to the triclinic system,P-1 space group,and forms 3D supramolecular structure through intermolecular hydrogen bonding;SNUT-2 belongs to monoclinic crystal,P2(1)/c space group,forming 1D chains between molecules and eventually becoming 1D framework structure.The results of bacteriostatic test show that the SNUT-1 has good bacteriostatic effect on both Escherichia coli and Staphylococcus aureus.

关 键 词：Cu(Ⅱ)配合物 晶体结构 抑菌 

分 类 号：O641.4[理学—物理化学]