肿瘤标志物检测在浆膜腔积液性质鉴别中的应用分析  

Application Analysis of Tumor Marker Detection in Identification of SerousCavity Effusion

作　　者：赵奕 张莹[1] 金云剑 ZHAO Yi;ZHANG Ying;JIN Yunjian(Laboratory Department,Baotou City Tumor Hospital,Baotou,Inner Mongolia 014030)

机构地区：[1]包头市肿瘤医院检验科,内蒙古包头014030

出　　处：《智慧健康》2023年第2期14-16,21,共4页Smart Healthcare

摘　　要：目的 分析肿瘤标志物检测在浆膜腔积液性质鉴别中的应用。方法 选取2020年3月-2021年5月本院收治的浆膜腔积液患者66例作为研究对象,经脱落细胞查找癌细胞法判定,良性为34例并将其设为良性组,恶性为32例设为恶性组,两组均给予肿瘤标志物检测,对比两组肿瘤标志物阳性率、各项标志物水平。结果 恶性组肿瘤标志物阳性率为96.88%,显著高于良性组5.88%(P<0.05)。恶性组CA125指标与良性组对比无明显差异(P>0.05);恶性组AFP、CEA、CA153、CA199、CA724、NSE、SCC、CYFRA21-1指标均高于对照组,差异显著(P<0.05)。结论 浆膜腔积液性质鉴别中使用肿瘤标志物检测对于良性、恶性的判断具有一定价值,其中恶性浆膜腔积液检测中肿瘤标志物相应指标升高显著,可对疾病判断起到一定指导作用。Objective To analyze application of tumor marker detection in identification of serous cavity effusion.Methods The paper chose 66 patients with serous cavity effusion from March 2020 to May 2021 as study subjects,34 cases with benign and 32 cases with malignant were included in benign group and malignant group by exfoliated cells.Both groups were tested for tumor markers.Positive rate of tumor markers and various markers level was compared between two groups.Results Positive rate of tumor markers in malignant group was 96.88%,which was significantly higher than benign group(5.88%,P<0.05).CA125 index in malignant group was significantly higher than benign group,with no significant difference(P>0.05);indexes of AFP,CEA,CA153,CA199,CA724,NSE,SCC,CYFRA21-1 in malignant group were significantly higher than control group(P<0.05),with significant difference.Conclusion Detection of tumor markers has certain value in diagnosis of benign and malignant in identification of serous effusion.Corresponding indicators of tumor markers increase significantly in detection of malignant serous effusion,which can play guiding role in diagnosis of disease.

关 键 词：肿瘤 标志物检测 浆膜腔积液 

分 类 号：R730.4[医药卫生—肿瘤]