经皮肝穿刺胆道引流/胆道支架植入术治疗肝外胆管癌合并梗阻性黄疸的研究进展  

Percutaneous transhepatic cholangial drainage/percutaneous transhepatic biliary stent implantation for treatment of extrahepatic cholangiocarcinoma with obstructive jaundice

作　　者：陈悦 张超[1] 罗涛[1] Yue Chen;Chao Zhang;Tao Luo(Department of General Surgery,Xuanwu Hospital,Capital Medical University,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院普通外科,北京市100053

出　　处：《世界华人消化杂志》2023年第5期165-171,共7页World Chinese Journal of Digestology

摘　　要：肝外胆管癌(extrahepatic cholangiocarcinoma,ECC)是起源于肝外胆管包括肝门区至胆总管下端胆管的恶性肿瘤,确诊时胆道受侵犯压迫常合并出现梗阻性黄疸,患者多处于中晚期而丧失根治性切除机会.随着介入技术及医学材料的发展,经皮肝穿刺胆道引流术(percutaneous transhepatic cholangial drainage,PTCD)或胆道支架植入术(percutaneous transhepatic biliary stent,PTBS)已成为解除胆道梗阻的主要治疗方法.然而,术后并发症的发生严重影响患者的预后,目前发现胆道支架联合局部治疗可显著延长胆道通畅时间.本文综述关于PTCD/PTBS治疗肝外胆管癌合并梗阻性黄疸的进展,评价其临床疗效,并指出目前存在的问题及处理方法,为后续相关研究提供更多参考.Extrahepatic cholangiocarcinoma is a malignant tumor originating from the extrahepatic bile duct including the hilar region to the lower bile duct of the common bile duct.With the development of interventional techniques and medical materials,percutaneous transhepatic cholangial drainage(PTCD)or percutaneous transhepatic biliary stent implantation(PTBS)has become the main treatment to relieve biliary obstruction.However,the occurrence of postoperative complications seriously affects the prognosis of patients,and the combination of biliary stenting with local treatment has been found to significantly prolong the time to biliary patency.This article reviews the progress of PTCD/PTBS in the treatment of extrahepatic cholangiocarcinoma with obstructive jaundice,evaluates its clinical efficacy,and points out the current problems and posible solutions to provide more reference for subsequent related studies.

关 键 词：肝外胆管癌 梗阻性黄疸 经皮肝穿刺胆道引流术 经皮肝穿刺胆道支架植入术 并发症 联合局部治疗 

分 类 号：R735.8[医药卫生—肿瘤]