内镜窄带成像技术在结直肠癌及癌前病变诊断中的应用价值  

Application value of endoscopic narrow band imaging in diagnosis of colorectal cancer and precancerous lesions

作　　者：李进 寇琼亚 张丽娜 LI Jin;KOU Qiongya;ZHANG Lina(Endoscopic Center of Luohe Traditional Chinese Medicine Hospital,Luohe 462000 Henan,China)

机构地区：[1]漯河市中医院内镜中心,河南漯河462000

出　　处：《中国民康医学》2023年第5期131-133,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察内镜窄带成像(NBI)技术在结直肠癌及癌前病变诊断中的应用价值。方法:选取2019年3月至2021年4月于该院行结直肠镜检查的72例疑似结直肠癌及癌前病变患者进行前瞻性研究,均采用常规内镜检查、NBI检查和病理检查,以病理检查结果作为“金标准”,采用Kappa检验分析NBI检查、常规内镜检查鉴别诊断早期结直肠癌、癌前病变和良性病变与病理检查的一致性,并比较NBI检查与常规内镜检查诊断早期结直肠癌、癌前病变的效能。结果:病理检查结果显示,72例疑似结直肠癌及癌前病变患者中,结直肠癌39例,癌前病变25例,良性病变8例。Kappa检验结果显示,常规内镜检查与病理检查诊断早期结直肠癌及癌前病变结果的一致性尚可(Kappa值=0.601,P=0.000);NBI检查与病理检查诊断早期结直肠癌及癌前病变结果的一致性良好(Kappa值=0.904,P=0.000)。NBI检查诊断结直肠癌的灵敏度、准确度均高于常规内镜检查,差异有统计学意义(P<0.05);NBI检查诊断结直肠癌前病变的准确度为98.61%,高于常规内镜检查的86.11%,差异有统计学意义(P<0.05)。结论:NBI检查与病理检查诊断早期结直肠癌及癌前病变结果的一致性良好,且NBI检查诊断结直肠癌的灵敏度、准确度以及诊断结直肠癌前病变的准确度高于常规内镜检查。Objective:To observe application value of endoscopic narrow band imaging(NBI)in diagnosis of colorectal cancer and precancerous lesions.Methods:A prospective study was conducted in 72 patients with suspected colorectal cancer and precancerous lesions who underwent colonoscopy from March 2019 to April 2021.Routine endoscopy,NBI and pathological examination were performed,and their results were observed.Using the results of pathological examination as“gold standard”,Kappa test was used to analyze the consistency between NBI,conventional endoscopy and pathological examination in the differential diagnosis of early colorectal cancer,precancerous lesions and benign lesions,and to compare the efficacies of NBI and conventional endoscopy in the diagnosis of early colorectal cancer and precancerous lesions.Results:The pathological examination showed that of the 72 cases of suspected colorectal cancer and precancerous lesions,39 were colorectal cancer,25 were precancerous lesions,and 8 were benign lesions.Kappa test showed that the consistency of results of routine endoscopy and pathological examination in the diagnosis of early colorectal cancer and precancerous lesions were fair(Kappa value=0.601,P=0.000);and the consistency of the results of NBI and pathological examination in the diagnosis of early colorectal cancer and precancerous lesions were good(Kappa value=0.904,P=0.000).The sensitivity and the accuracy of NBI in the diagnosis of colorectal cancer were higher than those of conventional endoscopy,and the differences were statistically significant(P<0.05).The accuracy of NBI in the diagnosis of colorectal precancerous lesions was 98.61%,which was higher than 86.11%of conventional endoscopy,and the differences were statistically significant(P<0.05).Conclusions:The consistency of the results of NBI and pathological examination in the diagnosis of early colorectal cancer and precancerous lesions are good.The sensitivity and the accuracy of NBI in the diagnosis of colorectal cancer and in the diagnosis of colorect

关 键 词：结直肠癌 癌前病变 内镜窄带成像 检查 诊断效能 

分 类 号：R735.3[医药卫生—肿瘤] R735.3[医药卫生—临床医学]