丁苯酞氯化钠注射液治疗血管性痴呆的疗效观察  

Efficacy observation of butylphthalide and sodium chloride injection in the treatment of vascular dementia

作　　者：张华 ZHANG Hua(Department of Neurology,Nuclear Industry General Hospital of Liaoning Health Industry Group,Huludao 125000,China)

机构地区：[1]辽宁省健康产业集团核工业总医院神经内科,125000

出　　处：《中国现代药物应用》2023年第5期137-139,共3页Chinese Journal of Modern Drug Application

摘　　要：目的观察丁苯酞氯化钠注射液治疗血管性痴呆的疗效。方法62例血管性痴呆患者,按照双色球随机分组法分为对照组与实验组,每组31例。对照组给予常规治疗,实验组在对照组治疗基础上应用丁苯酞氯化钠注射液治疗。比较两组临床治疗效果及不良反应发生情况。结果实验组治疗总有效率96.77%高于对照组70.97%,差异有统计学意义(P<0.05)。实验组不良反应发生率12.90%略高于对照组的9.68%,但差异无统计学意义(P>0.05)。结论血管性痴呆患者采用丁苯酞氯化钠注射液治疗可显著提升治疗效果,用药安全性较高。Objective To observe the efficacy of butylphthalide and sodium chloride injection in the treatment of vascular dementia.Methods A total of 62 cases of vascular dementia patients were randomly divided into control group and experimental group according to the two-color ball method,with 31 cases in each group.The control group was treated with conventional treatment,and the experimental group was treated with butylphthalide and sodium chloride injection on the basis of the control group.The clinical effects and occurrence of adverse reactions of the two groups were compared.Results The total effective rate of the experimental group was 96.77%,which was higher than 70.97%of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the experimental group was 12.90%,which was a little higher than 9.68%in the control group,but the difference was not statistically significant(P>0.05).Conclusion Butylphthalide and sodium chloride injection in the treatment of vascular dementia can significantly improve the therapeutic effect,with high safety.

关 键 词：血管性痴呆 丁苯酞氯化钠注射液 临床疗效 不良反应 

分 类 号：R749.13[医药卫生—神经病学与精神病学]