吲哚菁绿荧光实时成像技术在甲状腺癌根治术淋巴结清扫过程中的应用效果  

Application Effect of Indocyanine Green Fluorescence Real-time Imaging Technology in Lymph Node Dissection of Radical Thyroidectomy

作　　者：陈永安[1] 王亦璜 黄小荣[1] 梅倩 CHEN Yongan;WANG Yihuang;HUANG Xiaorong;MEI Qian(Fuding City Hospital,Fuding 355200,Fujian,China)

机构地区：[1]福建省福鼎市医院,福建福鼎355200

出　　处：《中国药物滥用防治杂志》2023年第1期92-94,共3页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:分析吲哚菁绿荧光实时成像技术在甲状腺癌根治术淋巴结清扫中的应用效果。方法:选取2019年7月—2021年8月我院收治的60例患者作为研究对象。采用随机数字表法将患者分为对照组(甲状腺癌根治术+常规淋巴结清扫)和观察组(甲状腺癌根治术+吲哚菁绿注射),每组30例。比较两组淋巴结检出数量、血清指标[甲状旁腺激素(parathyroid hormone,PTH)水平、血清钙]及不良反应发生情况。结果:观察组清扫淋巴结总体数量、微小淋巴结数量均高于对照组(P<0.05);两组PTH、血清钙水平,差异无统计学意义(P>0.05);两组术后均未发生声音嘶哑、声调变低以及麻木抽搐等低钙症状,临床治疗安全性高。结论:吲哚菁绿荧光实时成像技术在甲状腺癌根治术淋巴结清扫中的应用价值更高,可提升中央区淋巴结清扫的淋巴结检出数量,且安全性高,无不良反应发生应用概率。Objective: To analyze the application effect of indocyanine green fluorescence real-time imaging technology in lymph node dissection of radical thyroidectomy. Methods: A lot of 60 patients admitted to our hospital from July 2019 to August 2021 were selected as the study subjects. The patients were divided into control group(radical resection of thyroid cancer + routine lymph node dissection) and observation group(thyroid carcinoma radical resection+green green injection)with 30 patients in each group. The number of lymph nodes detected, serum indexes [parathyroid hormone(PTH) level,serum calcium] and the occurrence of adverse reactions in the two groups were compared. Results: The overall number of dissected lymph nodes and the number of tiny lymph nodes in the observation group were higher than that in the control group(P<0.05). There was no significant difference in PTH and serum calcium levels between the two groups(P>0.05).There were no low calcium symptoms such as hoarseness, low tone and numbness and convulsions in the two groups after operation, and the safety of clinical treatment was high. Conclusion: The application value of indocyanine green fluorescence real-time imaging technology in lymph node dissection of radical thyroidectomy is higher, which can improve the number of lymph nodes detected in central lymph node dissection, with high safety and no incidence of adverse reactions.

关 键 词：吲哚菁绿 荧光 实时成像 甲状腺癌 根治术 淋巴结清扫 

分 类 号：R736.1[医药卫生—肿瘤]