派丽奥联合牙周基础治疗慢性牙周炎患者的疗效  

Efficacy of Periocline Combined with Periodontal Basic Treatment in Patients with Chronic Periodontitis

作　　者：刘努 范莹莹 顾圣祖 LIU Nu;FAN Yingying;GU Shengzu(Department of Periodontics,Kunshan Tinglin Stomatological Hospital,Kunshan 215300,Jiangsu,China)

机构地区：[1]昆山亭林口腔医院牙周科,江苏昆山215300

出　　处：《中国药物滥用防治杂志》2023年第1期139-143,共5页Chinese Journal of Drug Abuse Prevention and Treatment

基　　金：昆山市社会发展科技专项课题(编号:KSZ2266)。

摘　　要：目的:探究派丽奥联合牙周基础治疗慢性牙周炎患者的疗效。方法:选取2020年5月—2022年5月本院门诊收治的84例慢性牙周炎患者作为研究对象,并按随机数字表法分成对照组(42例)和联合组(42例)。对照组行牙周基础治疗,联合组在行牙周基础治疗基础上结合派丽奥治疗,比较两组临床疗效、牙周指标[牙龈指数(GI)、牙周袋深度(PD)、菌斑指数(PLI)、牙周附着水平(AL)、牙齿松动度(TM)]、药物使用依从性、不良反应发生率及随访6个月后牙周炎复发率。结果:联合组治疗后总有效率为95.24%,高于对照组的78.57%(P<0.05);两组治疗后GI、PD、PLI、AL、TM水平均低于治疗前,且联合组低于对照组(P<0.05);两组治疗后药物使用依从性评分高于治疗前,且联合组高于对照组(P<0.05);联合组不良反应发生率低于对照组,但差异无统计学意义(P>0.05);随访结束后,联合组牙周炎复发率低于对照组(P<0.05)。结论:派丽奥联合牙周基础治疗能提高慢性牙周炎患者的疗效和药物使用依从性,改善牙周指标,降低牙周炎复发率,促进牙龈健康,值得临床应用。Objective: To explore the effects of periocline combined with periodontal initial therapy on periodontal indexes and periodontitis recurrence in patients with chronic periodontitis. Methods: A total of 84 patients with chronic periodontitis admitted to outpatient department of the hospital were enrolled as the research objects between May 2020 and May 2022.According to random number table method, they were divided into control group(42 cases) and combination group(42cases). The control group was given periodontal initial therapy, while combination group was additionally treated with periocline. The clinical curative effect, periodontal indexes [gingival index(GI), pocket depth(PD), plaque index(PLI),attachment loss(AL), tooth mobility(TM)], medication compliance, incidence of adverse reactions and recurrence rate of periodontitis after 6 months of follow-up were compared between the two groups. Results: The total response rate of treatment in combination group was higher than that in control group(95.24% vs 78.57%, P<0.05). After treatment, levels of GI, PD, PLI, AL and TM in both groups were decreased, which were lower in combination group than control group(P<0.05).After treatment, score of medication compliance in both groups was increased, which was higher in combination group than control group(P<0.05). The incidence of adverse reactions in combination group was lower than that in control group, but the difference was not statistically significant(P>0.05). After follow-up, recurrence rate of periodontitis in combination group was lower than that in control group(P<0.05). Conclusion: Periocline combined with periodontal initial therapy can improve curative effect, medication compliance and periodontal indexes, reduce recurrence rate of periodontitis and promote gingival health in patients with chronic periodontitis.

关 键 词：派丽奥 牙周基础治疗 慢性牙周炎 牙周指标 牙周炎复发率 

分 类 号：R781.42[医药卫生—口腔医学]