Treatment of a large area perioral viral herpes infection following noninvasive ventilation:A case report  

作　　者：A-Mao Tang Jia-Ying Xu Rong Wang Yi-Min Li 

机构地区：[1]Department of Digestion,The Affiliated Hangzhou First People's Hospital,Zhejiang University School of Medicine,Hangzhou 310000,Zhejiang Province,China [2]Department of Nursing,The Affiliated Hangzhou First People's Hospital,Zhejiang University School of Medicine,Hangzhou 310006,Zhejiang Province,China

出　　处：《World Journal of Clinical Cases》2023年第8期1857-1861,共5页世界临床病例杂志

基　　金：Supported by the Construction Fund of Key Medical Disciplines of Hangzhou,No.OO20200265;the Basic Public Welfare Research Project of Zhejiang Province,No.LGF22H250005;General project of Hangzhou Health Science and Technology Plan,No.A20200320;Zhejiang Provincial Medical and Health Technology Project,No.2020PY016.

摘　　要：BACKGROUND Alphaherpesvirus belongs to the Herpesviridae family and has large,monopartite double-stranded linear DNA.It mainly infects the skin,mucosa,and nerves,and can affect various hosts,including humans and other animals.Here,we present a case of a patient seen by the gastroenterology department at our hospital who experienced an oral and perioral herpes infection following treatment with a ven-tilator.The patient was treated with oral and topical antiviral drugs,furacilin,oral and topical antibiotics,local epinephrine injection,topical thrombin powder,and nutritional and supportive care.A wet wound healing approach was also implemented with good response.CASE SUMMARY A 73-year-old woman presented to the hospital with a chief complaint of"abdominal pain for 3 d with dizziness for 2 d."She was admitted to the intensive care unit for septic shock and spontaneous peritonitis secondary to cirrhosis and was given antiinflammatory and symptomatic supportive treatment.A ventilator was used to assist breathing for acute respiratory distress syndrome,which developed during her admission.A large area of herpes infection appeared in the perioral region 2 d following noninvasive ventilation.The patient was transferred to the gastroenterology department,at which time she had a body temperature of 37.8 C and a respiratory rate of 18/min.The patient's con-sciousness was intact,and she no longer had abdominal pain or distension,chest tightness,or asthma.At this point,the infected perioral region changed in appearance and was now accompanied by local bleeding with crusting of blood at the wounds.The surface area of the wounds measured approximately 10 cm×10 cm.A cluster blisters appeared on the patient’s right neck,and ulcers developed in her mouth.On a subjective numerical pain scale,the patient reported a pain level of 2.Overall,her diagnoses other than the oral and perioral herpes infection included:(1)Septic shock;(2)spontaneous peritonitis;(3)abdominal infection;(4)decompensated cirrhosis;and(5)hypoproteinemia.Dermat

关 键 词：VENTILATOR Viral herpes Nursing care Case report 

分 类 号：R781.53[医药卫生—口腔医学]