Autoimmune encephalitis after surgery for appendiceal cancer:A case report  

作　　者：Yan-Hui Mao Lu Li Li-Ming Wen Jia-Min Qin Ya-Ling Yang Li Wang Fan-Rong Wang Yi-Zhou Zhao 

机构地区：[1]Department of Gastroenterology,Sichuan Mianyang 404 Hospital,Mianyang 621000,Sichuan Province,China [2]Department of Pathology,Sichuan Mianyang 404 Hospital,Mianyang 621000,Sichuan Province,China [3]Department of Medical Imaging,Sichuan Mianyang 404 Hospital,Mianyang 621000,Sichuan Province,China

出　　处：《World Journal of Clinical Cases》2023年第11期2576-2581,共6页世界临床病例杂志

摘　　要：BACKGROUND Primary cancer of the appendix is rare and often difficult to diagnose preoperatively due to the lack of specific clinical symptoms. Autoimmune encephalitis(AIE) is the most common cause of non-infectious encephalitis. The etiologies of AIE include tumors(paraneoplastic), infections(parainfections), or recessive infections. The tumors that have been reported to cause AIE include thymomas, ovarian teratomas, lung cancers, and breast cancers. However, there are no reports of AIE occurring after surgery for appendiceal cancer. This report describes the diagnosis and treatment of a patient with an appendiceal cancer and postoperative AIE.CASE SUMMARY We report the case of a 47-year-old man who was transferred to our hospital due to a recurrent low intestinal obstruction. Abdominal enhanced computed tomography was used to consider the possibility of a terminal ileal tumor with serous infiltration and lymph node metastasis. A right hemi-colectomy was performed under general anesthesia with an ileo-transcolon anastomosis and laparoscopic exploration. The postoperative pathologic evaluation revealed a high-grade goblet cell carcinoma of the appendix, accompanied by mesangial and abdominal lymph node metastases, and neural tube and vascular infiltration. The operation was completed without complication. The patient developed restlessness on postoperative day 4, and gradually developed a disturbance of consciousness on postoperative day 6. He was transferred to West China Hospital of Sichuan University and diagnosed with AIE.CONCLUSION Albeit rare, the occurrence of neurologic and psychiatric symptoms in patients with an appendiceal cancer postoperatively suggests the possibility of AIE.

关 键 词：Appendiceal cancer Goblet cell carcinoma Repeated ileus POSTOPERATIVE Autoimmune encephalitis Case report 

分 类 号：R735.36[医药卫生—肿瘤] R742.9[医药卫生—临床医学]