Role of hematological parameters in pathogenesis of diabetes mellitus:A review of the literature  

作　　者：Sana Rafaqat Saira Rafaqat 

机构地区：[1]Department of Biotechnology,Lahore College for Women University,Lahore 5400,Pakistan [2]Department of Zoology,Lahore College for Women University,Lahore 5400,Pakistan

出　　处：《World Journal of Hematology》2023年第3期25-41,共17页世界血液学杂志

摘　　要：Diabetes mellitus(DM)is characterized by hyperglycemia and abnormalities in insulin secretion and activity.There are numerous hematological parameters;however,this review article only focuses on red blood cells,hemoglobin,hematocrit,red blood cell indices,platelet count,white blood cells,lymphocytes,neutrophils,monocytes,eosinophils,neutrophil-to-lymphocyte ratio,platelet-to-lymphocyte ratio,and monocyte-to-lymphocyte ratio,which play an essential role in the pathogenesis of DM.Also,this review article aims to report the relationship between these hematological parameters and the development of DM.In con-clusion,this article shows that increased levels of platelets,red blood cells,hematocrit,lymphocytes,eosinophils,neutrophils,neutrophil-to-lymphocyte ratio,platelet-to-lymphocyte ratio,and monocyte-to-lymphocyte ratio and decreased levels of hemoglobin are involved in the pathogenesis of DM.However,the role of basophils in DM is unknown yet.

关 键 词：Hematological parameters Diabetes mellitus PATHOGENESIS Type 2 diabetes mellitus 

分 类 号：R58[医药卫生—内分泌]