Medium-term surgical outcomes and health-related quality of life after laparoscopic vs open colorectal cancer resection: SF-36 health survey questionnaire  

作　　者：Chao-Ming Hung Kuo-Chuan Hung Hon-Yi Shi Shih-Bin Su Hui-Ming Lee Meng-Che Hsieh Cheng-Hao Tseng Shung-Eing Lin Chih-Cheng Chen Chao-Ming Tseng Ying-Nan Tsai Chi-Zen Chen Jung-Fa Tsai Chong-Chi Chiu 

机构地区：[1]Department of General Surgery,E-Da Cancer Hospital,I-Shou University,Kaohsiung 82445,Taiwan,China [2]School of Medicine,College of Medicine,I-Shou University,Kaohsiung 82445,Taiwan,China [3]Department of Anesthesiology,Chi Mei Medical Center,Tainan 71004,Taiwan,China [4]Department of Hospital and Health Care Administration,College of Recreation and Health Management,Chia Nan University of Pharmacy and Science,Tainan 71710,Taiwan,China [5]Department of Healthcare Administration and Medical Informatics,Kaohsiung Medical University,Kaohsiung 80708,Taiwan,China [6]Department of Business Management,National Sun Yat-Sen University,Kaohsiung 80424,Taiwan,China [7]Department of Medical Research,Kaohsiung Medical University Hospital,Kaohsiung 80756,Taiwan,China [8]Department of Medical Research,China Medical University Hospital,China Medical University,Taichung 40402,Taiwan,China [9]Department of Occupational Medicine,Chi Mei Medical Center,Liouying 73657,Taiwan,China [10]Department of Occupational Medicine,Chi Mei Medical Center,Tainan 71004,Taiwan,China [11]Department of Leisure,Recreation and Tourism Management,Southern Taiwan University of Science and Technology,Tainan 71005,Taiwan,China [12]College of Medicine,I-Shou University,Kaohsiung 82445,Taiwan,China [13]Department of Hematology-Oncology,E-Da Cancer Hospital,I-Shou University,Kaohsiung 82445,Taiwan,China [14]Department of Gastroenterology and Hepatology,E-Da Cancer Hospital,I-Shou University,Kaohsiung 82445,Taiwan,China [15]Department of Gastroenterology and Hepatology,E-Da Hospital,I-Shou University,Kaohsiung 82445,Taiwan,China [16]Department of Colon and Rectal Surgery,E-Da Cancer Hospital,I-Shou University,Kaohsiung 82445,Taiwan,China [17]Department of Gastroenterology and Hepatology,E-Da Dachang Hospital,I-Shou University,Kaohsiung 80794,Taiwan,China [18]Department of Medical Education and Research,E-Da Cancer Hospital,I-Shou University,Kaohsiung 82445,Taiwan,China [19]Department of General Surgery,Chi Mei Medical Center,Liouying 73657,Taiwan,China

出　　处：《World Journal of Gastrointestinal Endoscopy》2023年第3期163-176,共14页世界胃肠内镜杂志（英文版）（电子版）

基　　金：Supported by The Research Foundation of E-Da Cancer Hospital and E-Da Hospital,Kaohsiung,Taiwan,No.EDCHI111002 and NCKUEDA11110.

摘　　要：BACKGROUND Previous studies that compared the postoperative health-related quality of life(HRQoL)outcomes after receiving laparoscopic resection(LR)or open resection(OR)in patients with colorectal cancer(CRC)have different conclusions.AIM To explore the medium-term effect of postoperative HRQoL in such patients.METHODS This study randomized 567 patients undergoing non-metastatic CRC surgery managed by one surgeon to the LR or OR groups.HRQoL was assessed during the preoperative period and 3,6,and 12 mo postoperative using a modified version of the 36-Item Short Form(SF-36)Health Survey questionnaire,emphasizing eight specific items.RESULTS This cohort randomly assigned 541 patients to receive LR(n=296)or OR(n=245)surgical procedures.More episodes of postoperative urinary tract infection(P<0.001),wound infection(P<0.001),and pneumonia(P=0.048)were encountered in the OR group.The results demonstrated that the LR group subjectively gained mildly better general health(P=0.045),moderately better physical activity(P=0.006),and significantly better social function recovery(P=0.0001)3 mo postoperatively.Only the aspect of social function recovery was claimed at 6 mo,with a significant advantage in the LR group(P=0.001).No clinical difference was found in HRQoL during the 12 mo.CONCLUSION Our results demonstrated that LR resulted in better outcomes,including intra-operative blood loss,surgery-related complications,course of recovery,and especially some health domains of HRQoL at least within 6 mo postoperatively.Patients should undergo LR if there is no contraindication.

关 键 词：Health-related quality of life Medium-term result LAPAROSCOPIC Open surgery Non-metastatic colorectal cancer 

分 类 号：R735.34[医药卫生—肿瘤]