OCT测量黄斑区神经节细胞复合体厚度在高度近视眼中的应用进展  

Application progress of OCT measurement for ganglion cell complex thickness in high myopic eyes

作　　者：范圆媛 谢平(综述)[1] 胡仔仲(审校) FAN Yuanyuan;XIE Ping;HU Zizhong(Department of Ophthalmology,The First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学第一附属医院,南京210029

出　　处：《眼科学报》2023年第3期274-286,共13页Eye Science

基　　金：国家自然科学资金青年项目(81900875)。

摘　　要：近视防控已经上升到我国国家战略层面,高度近视引起的视神经病变会损害视功能,但在临床上常常被忽视。OCT可以非侵入、高分辨率、快速以及可重复地定量视网膜各层厚度,是评估高度近视相关视神经病变的有力工具。由于高度近视常合并视盘和盘周的改变,视神经纤维层厚度的定量常出现误差。近年来,学者开始聚焦于黄斑区神经节细胞复合体(ganglion cell complex,GCC)厚度的研究,但其在高度近视眼中的变化规律尚不统一。该文针对近年来高度近视眼黄斑区GCC的测量规范、诊断价值、变化规律等进行综述,以期提高眼科医师对高度近视视神经病变的重视和研究水平。Myopia prevention and control has risen to the national strategic level in China.Optic neuropathy caused by high myopia can damage visual function,but it is often ignored in clinical practice Optical coherence tomography(OCT) characterized by non-invasiveness, high resolution, rapid, and repeatable quantifying the thickness of each layer in the retina has emerged as a powerful tool for evaluating high myopia related optic neuropathy. Due to the changes in and near the optic disc in high myopia, errors often occur in the quantification of the thickness of the optic nerve fiber layer. In recent years, researchers have gradually focused on the study of the thickness of ganglion cell complex (GCC), but the regularity of its changes in high myopia is not yet unified. This article reviews the measurement specifications, diagnostic values, and change rules of GCC in the macular region of high myopia in recent years, in order to improve the attention and research level of ophthalmologists on high myopia optic neuropathy.

关 键 词：黄斑区神经节细胞复合体 高度近视 光学相干断层扫描 视网膜神经纤维层 

分 类 号：R778.11[医药卫生—眼科]