无症状型烟雾病的研究进展  

Research progress of asymptomatic moyamoya disease

作　　者：刘尚宽 陈月芹[2] LIU Shangkuan;CHEN Yueqin(Clinical School,Jining Medical University,Jining 272013,China;Affiliated Hospital of Jining Medical University,Jining 272029,China)

机构地区：[1]济宁医学院临床医学院,山东济宁272013 [2]济宁医学院附属医院,山东济宁272029

出　　处：《中国实用神经疾病杂志》2023年第3期388-391,共4页Chinese Journal of Practical Nervous Diseases

基　　金：山东省自然科学基金(编号:ZR2021MH109);济宁市重点研发计划(社会民生类)项目(编号:2020YXNS024);济宁市重点研发计划(软科学)项目(编号:2022JNZC088)。

摘　　要：烟雾病(moyamoya disease,MMD)是一种病因不明、慢性进展性脑血管疾病,主要表现为双侧颈内动脉末端进行性狭窄和侧支循环的发展,临床表现主要分为出血型及缺血型。随着非侵入性磁共振检查的发展,无症状型MMD的患病率逐渐增加,其在发展过程中也可发生脑血管事件,但是由于患者数量少和随访周期短,其相关的管理指南尚未建立。本文整理了关于国内外无症状型MMD的文献资料,综述其临床特征、预后和管理策略,以期为临床的诊断及精准诊疗提供参考。Moyamoya disease(MMD)is a chronic progressive cerebrovascular disease of unknown etiology,which is mainly characterized by progressive stenosis of bilateral internal carotid arteries and the development of collateral circulation,the clinical manifestations are mainly divided into hemorrhagic and ischemic types.With the development of non-invasive magnetic resonance imaging,the prevalence of asymptomatic MMD has gradually in⁃creased,and cerebrovascular events can also occur during the development process.However,due to the small number of patients and the short follow-up period,asymptomatic MMD management guidelines have not yet been established.This article summarizes the literature on asymptomatic MMD at home and abroad,summarizes its clini⁃cal characteristics,prognosis and management strategies,in order to provide reference for clinical diagnosis and precise diagnosis and treatment.

关 键 词：烟雾病 无症状 影像学 预后 

分 类 号：R743.4[医药卫生—神经病学与精神病学]