视神经炎患者激素治疗引起牙酸蚀症1例  

Dental erosion caused by glucocorticoid therapy in a patient with optic neuritis:a case report

作　　者：商梦瑶 魏雨奇 于美娇 张瑾 崔平平 Shang Mengyao;Wei Yuqi;Yu Meijiao;Zhang Jin;Cui Pingping(Dept.of Endodontics,School and Hospital of Stomatology,Cheeloo College of Medicine,Shandong University&Shandong Provincial Key Laboratory of Oral Tissue Regeneration&Shandong Provincial Engineering Laboratory for Dental Materials and Oral Tissue Regeneration&Shandong Provincial Clinical Research Center for Oral Diseases,Jinan 250012,China)

机构地区：[1]山东大学齐鲁医学院口腔医学院·口腔医院牙体牙髓科、山东省口腔组织再生重点实验室山东省口腔生物材料与组织再生工程实验室、山东省口腔疾病临床医学研究中心,济南250012

出　　处：《华西口腔医学杂志》2023年第2期243-246,共4页West China Journal of Stomatology

基　　金：山东省重点研发计划(2019GSF108005)。

摘　　要：牙酸蚀症是指牙齿受到不涉及细菌的化学物质侵蚀使得牙齿硬组织发生进行性破坏的一种疾病。病因包括内在因素和外在因素,内在因素如暴食、厌食、胃肠道疾病、药物等导致的胃食管反流而引起的牙齿酸蚀,外在因素则主要包括饮食、药物、职业因素等。本文介绍了1位患者,因诊断为视神经炎而接受糖皮质激素治疗,从而引起胃食管反流症状,出现全口牙齿尤其是上颌牙列的重度酸蚀破坏。本文主要就视神经炎激素治疗与牙酸蚀症发生的机制进行了探讨。Dental erosion is characterized by progressively destroyed teeth,which has no relation to bacteria but to chemicals.Some internal factors,such as gastroesophageal reflux induced by bulimia,anorexia,gastrointestinal diseases,or drugs,and external factors,such as diet,drugs,and occupational acid exposure,are considered promotive factors for this disease.This article presents a patient suffering from severe dental erosion in the whole dentition,especially in the maxillary teeth,due to gastroesophageal reflux induced by glucocorticoid therapy for optic neuritis.This article discusses the mechanism between optic neuritis glucocorticoid therapy and dental erosion.

关 键 词：牙酸蚀症 视神经炎 胃食管反流 糖皮质激素 

分 类 号：R781.2[医药卫生—口腔医学]