脉络膜毛细血管流空的临床应用研究进展  

Research progress in clinical application of choroid capillary flow deficits

作　　者：毕萌 樊芳[1] 贾志旸[1] BI Meng;FAN Fang;JIA Zhiyang(Department of Ophthalmology,Hebei General Hospital,Shijiazhuang 050051,China;Graduate School,North China University of Science and Technology)

机构地区：[1]河北省人民医院眼科,050051 [2]华北理工大学研究生院

出　　处：《天津医药》2023年第4期445-448,共4页Tianjin Medical Journal

基　　金：河北省医学适用技术跟踪项目(GZ2021040)。

摘　　要：随着光学相干断层扫描血管成像技术(OCTA)的发展,运用OCTA定量分析脉络膜毛细血管(CC)情况已经成为一种新兴的评估手段。视网膜及脉络膜等眼部相关疾病的发生发展与脉络膜血管的形态及功能密切相关,尤其与脉络膜毛细血管的变化有关。通过OCTA获得的CC层图像进行二值化处理及量化分析后,可得到测量范围内CC层流空区域数量、面积、百分比等参数,从而评估脉络膜毛细血管血流灌注变化情况,对探索相关疾病的发病机制、疾病的诊断及干预治疗提供一定的帮助。就脉络膜毛细血管流空区域的临床应用研究进展进行综述。With the development of optical coherence tomography(optical coherence tomography angiography,OCTA),quantitative study of choriocapillaris(choriocapillaris,CC)has become a novel evaluation method.The occurrence and development of eye diseases,such as retina and choroid are closely related to the morphology and function of choroidal vessels,especially the change of choriocapillaris.The CC flow deficits parameters,such as density,area and number can be obtained after processing and quantitative analysising images of CC layer from OCTA,assess changes in choroid blood capillary perfusion,explore the pathogenesis of related diseases and provide certain help for disease diagnosis and intervention therapy.This paper reviews the clinical application and research progress of choroid capillary flow deficits.

关 键 词：脉络膜 毛细血管 体层摄影术 光学相干 脉络膜血流不足 中心性浆液性视网膜脉络膜病变 年龄相关性黄斑变性 

分 类 号：R773.4[医药卫生—眼科]