无赤光血管造影在眼底疾病检查中的图像特征研究  

Comparative study of image features of red-free angiography in the examination of fundus diseases

作　　者：张慧[1] 张馨月 张含[1] ZHANG Hui;ZHANG Xinyue;ZHANG Han(Department of Ophthalmology,The First Hospital of China Medical University,Shenyang 110001,China)

机构地区：[1]中国医科大学附属第一医院眼科,沈阳110001

出　　处：《中国医科大学学报》2023年第3期247-252,共6页Journal of China Medical University

基　　金：辽宁省科学技术计划(2013225303)。

摘　　要：目的 探讨无赤光血管造影(RFA)与眼底荧光素血管造影(FFA)联合吲哚菁绿血管造影(ICGA)检查、光学相干断层成像检查(OCT)及眼底自发荧光检查(FAF)相比,在眼底病变检查中的优势。方法 采用RFA、FFA、ICGA、OCT和FAF对2022年1月至8月期间于中国医科大学附属第一医院就诊的29例(41眼)眼底病变患者进行检查,利用数据和检查图像比较几种检查方法的异同。结果 对于视网膜下积液的观察,RFA比FFA有优势,与ICGA晚期图像和OCT图像判读一致;对于视网膜神经纤维层状态的观察,RFA比FFA和ICGA晚期检查有优势;对于视乳头周围多灶性片状异常荧光病灶的观察,与FFA、ICGA晚期、FAF检查图像判读一致;对于视网膜点片状异常荧光的观察,RFA检查与ICGA晚期检查、FAF检查判读一致,比FFA检查有优势;对于黄斑区膜样高荧光的观察,RFA检查与OCT图像判读一致,比FFA、ICGA晚期检查有优势。结论 RFA检查在眼底病变的检查中,尤其是对视网膜下积液、视网膜神经纤维层等视网膜浅层结构的观察,比FFA、ICGA等检查方法更有优势。Objective To investigate the advantages of red-free angiography(RFA)compared with fundus fluorescein angiography(FFA)combined with indocyanine green angiography(ICGA),optical coherence tomography(OCT),and fundus autofluorescence(FAF)in the examination of fundus lesions.Methods Twenty-nine patients(41 eyes)with fundus lesions who visited the First Hospital of China Medical University from January,2022 to August,2022 were examined by RFA,FFA,ICGA,OCT,and FAF.The data and examination images were used to compare the similarities and differences of these examinations.Results For the observation of subretinal effusion,RFA has an advantage over FFA,which is consistent with the interpretation of late ICGA and OCT images.RFA has advantages over FFA and ICGA in the observation of retinal nerve fiber layer status.The observation of multifocal flak-like abnormal fluorescent lesions around the optic papilla was consistent with the interpretation of FFA,ICGA,and FAF images.For the observation of retinal patchy abnormal fluorescence,RFA is consistent with late phase ICGA and FAF,and has advantages over FFA.For the observation of membrane hyperfluorescence in the macular region,RFA is consistent with OCT image interpretation,and has advantages over FFA and late phase ICGA.Conclusion RFA has more advantages than FFA and ICGA in the examination of fundus lesions,especially in the observation of superficial retinal structures such as subretinal fluid and retinal nerve fiber layer.

关 键 词：无赤光血管造影 眼底荧光素血管造影 吲哚菁绿血管造影 眼底病变 

分 类 号：R770.41[医药卫生—眼科]