隐源性卒中患者的卵圆孔未闭:评价和二级预防  

Patent foramen ovale in patients with cryptogenic stroke:evaluation and secondary prevention

作　　者：王丽萍 宋秀娟[1] 迟冬雨 刘燕燕 万林姗 孙田新 张依格 张晗 Wang Liping;Song Xiujuan;Chi Dongyu;Liu Yanyan;Wan Linshan;Sun Tianxin;Zhang Yige;Zhang Han(The Second Hospital of Hebei Medical University,Hebei Provincial Key Laboratory of Neurology,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第二医院,河北省神经病学重点实验室,石家庄050000

出　　处：《国际脑血管病杂志》2022年第10期777-781,共5页International Journal of Cerebrovascular Diseases

基　　金：河北省医学科学研究课题(20211276)。

摘　　要：隐源性卒中(cryptogenic stroke,CS)是使用卒中标准临床检查程序之后,仍然不能找到确切病因的卒中类型。近年来,多项研究表明卵圆孔未闭(patent foramen ovale,PFO)与CS关系密切,其主要发病机制为反常性栓塞。在临床实践中,多使用超声方法进行PFO筛查。在PFO背景下,CS的二级预防包括药物治疗和PFO封堵术,但选择何种治疗方式目前仍存在着争议。针对可能存在的PFO进行筛查和评价,有助于为CS患者制定二级预防策略,特别是能从PFO封堵术中受益的患者。Cryptogenic stroke(CS)is a type of stroke that can not find the exact cause after using the standard clinical examination procedure of stroke.In recent years,many studies have shown that patent foramen ovale(PFO)is closely associated with CS,and its main pathogenesis is paradoxical embolism.In clinical practice,ultrasound is often used for PFO screening.In the context of PFO,the secondary prevention of CS includes drug therapy and PFO closure,but the choice of treatment is still controversial.Screening and evaluation of possible PFO will help to develop secondary prevention strategies for patients with CS,especially those who can benefit from PFO closure.

关 键 词：卒中 脑缺血 卵圆孔 未闭 超声心动描记术 超声检查 多普勒 经颅 危险因素 二级预防 

分 类 号：R743.3[医药卫生—神经病学与精神病学]