不同浓度肝素钠封管液应用于手臂输液港封管的效果比较  

Comparison of Sealing Effect of Different Concentrations of Heparin Sodium in the Port of Arm Infusion

作　　者：张素兰[1] 邢璐[1] 吕敏超 单唱 王佳琪 ZHANG Sulan;XING Lu;L Minchao;SHAN Chang;WANG Jiaqi(Department of Oncology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]郑州大学第一附属医院肿瘤科,河南郑州450000

出　　处：《河南医学研究》2023年第6期1113-1116,共4页Henan Medical Research

基　　金：河南省教育厅项目(23A320006)。

摘　　要：目的比较不同浓度肝素钠封管液应用于植入手臂输液港肿瘤患者中的临床效果。方法选取2021年12月至2022年9月在某三级甲等医院肿瘤科住院首次植入手臂输液港的肿瘤患者320例为研究对象。采用随机数字表法,将患者分为A、B两组,分别使用100 U·mL^(-1)肝素钠封管液和50 U·mL^(-1)肝素钠封管液各2 mL进行输液港封管。其中每组分a组和b组,a组在患者每次用药后和治疗周期结束时均使用10 mL预充式导管冲洗器和肝素钠封管液进行封管;b组在患者每次用药后仅使用10 mL预充式导管冲洗器封管,治疗周期结束时使用10 mL预充式导管冲洗器和肝素钠封管液封管。比较各组患者手臂输液港堵管和血栓发生率。结果各组手臂输液港堵管及血栓发生率比较,差异无统计学意义(P>0.05)。结论在患者每次用药后仅使用10 mL预充式导管冲洗器封管,治疗周期结束时使用10 mL预充式导管冲洗器和50 U·mL^(-1)肝素钠封管液2 mL封管能够满足治疗需要,不会导致患者手臂输液港堵管及血栓发生率的升高。Objective To compare the clinical effects of different concentrations of heparin sodium sealing solution in the tumor patients implanted in the arm infusion port.Methods A total of 320 patients who were admitted to the oncology department of a tertiary class A hospital from December 2021 to September 2022 for the first time and received arm infusion port implantation were selected as research objects.The patients were divided into group A and group B,the infusion port was sealed with 100 U·mL^(-1)heparin sodium sealing solution and 50 U·mL^(-1)heparin sodium sealing solution respectively.Each group was divided into group a and group b.In group a,10 mL pre-filled flush syringes and heparin sodium sealing solution were used to seal the tubes after each medication and at the end of the treatment cycle.In group b,only 10 mL pre-filled flush syringes was used to seal the tube after each medication,and 10 mL pre-filled flush syringes and heparin sodium sealing solution were used to seal the tube at the end of the treatment cycle.The incidence of tube occlusion and thrombosis in the arm infusion port of each group was compared.Results During the trial,there was no statistical significant in the incidence of tube occlusion and thrombosis in the arm infusion port among all groups(P>0.05).Conclusion Only 10 mL pre-filled flush syringes is used to seal the tube after each medication,and at the end of the treatment cycle,10 mL pre-filled flush syringes and 50 U·mL^(-1)heparin sodium sealing solution 2 mL sealing tube could meet the treatment needs.This method does not lead to an increase in the incidence of tube occlusion and thrombosis in the patient’s arm infusion port.

关 键 词：手臂输液港 肝素钠 封管 堵管 血栓形成 

分 类 号：R730.5[医药卫生—肿瘤]