基于“百病皆为痰作祟”理论探讨祛风导痰汤治疗续发性全身强直-阵挛性发作癫痫患者临床观察  

Effect Observation of Qufeng Daotan Decoction(祛风导痰汤)in Treatment of Patients with Recurrent Generalized Tonic Clonic SeizuresBased on Theory of“All Diseases Caused by Phlegm”

作　　者：王实[1] 刘姿瑶[2] 张小倩[1] 阎丽媚 WANG Shi;LIU Ziyao;ZHANG Xiaoqian;YAN Limei(The First Affiliated Hospital of China Medical University,Shenyang 110001,Liaoning,China;Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China)

机构地区：[1]中国医科大学附属第一医院,辽宁沈阳110001 [2]辽宁中医药大学附属医院,辽宁沈阳110032

出　　处：《辽宁中医杂志》2023年第3期78-81,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81801053)。

摘　　要：目的 基于“百病皆为痰作祟”理论探讨祛风导痰汤对续发性全身强直-阵挛性发作癫痫患者的临床疗效。方法 选取2018年1月—2020年3月续发性全身强直-阵挛性发作癫痫患者92例,随机分两组,对照组采用电子生物反馈技术;联合组采用基于“百病皆为痰作祟”理论的祛风导痰汤联合电子生物反馈技术,持续3个月。治疗后评价患者临床疗效、癫痫生活质量评定量表(quality of life rating scale for patients with epilepsy, QOLIE-31)、连线测验A-B、数字符号转换测验(digital symbol conversion test, DSST)、词语流畅性测验(verbal fluency test, VFT)、数字广度测验(digit span test, DST)等,比较两组不良反应。结果 对照组的有效率78.26%(36/46)低于联合组93.48%(43/46),有统计学意义(P<0.05)。对照组治疗3个月综合质量、情绪、总体健康、药物影响、认知功能、社会功能、精力、对发作担忧评分均低于联合组,有统计学意义(P<0.05)。对照组治疗3个月连线测验A、连线测验B高于联合组,DSST评分、VFT评分、DST评分低于联合组,有统计学意义(P<0.05)。对照组总不良反应率23.91%(11/46)与联合组28.26%(13/46)比较,无统计学意义(P>0.05)。结论 基于“百病皆为痰作祟”理论的祛风导痰汤对续发性全身强直-阵挛性发作癫痫患者的临床疗效显著,可以改善认知功能,从而提高生活质量。Objective Based on the theory that"all diseases are caused by phlegm",this paper discusses the clinical effect of Qufeng Daotan Decoction(祛风导痰汤)in the treatment of patients with recurrent generalized tonic clonic seizures.Methods Ninety-two patients with recurrent generalized tonic clonic seizures from January 2018 to March 2020 were randomly divided into two groups.Electronic biofeedback technology was used in the control group.The combined group adopted Qufeng Daotan Decoction combined with electronic biofeedback technology based on the theory that"all diseases are caused by phlegm"for 3 months.After treatment,the clinical efficacy,quality of life rating scale for patients with epilepsy(QOLIE-31),connection test A-B,digital symbol conversion test(DSST),verbal fluency test(VFT)and digital span test(DST)were evaluated,and the adverse reactions of the two groups were compared.Results The effective rate of the control group(78.26%,36/46)was significantly lower than that(93.48%,43/46)of the combined group(P<0.05).After 3 months of treatment,the scores of comprehensive quality,mood,overall health,drug impact,cognitive function,social function,energy and anxiety about attack in the control group were significantly lower than those in the combined group(P<0.05).After 3 months of treatment,the scores of connection test A and connection test B in the control group were higher than those in the combined group,and the scores of DSST,VFT and DST in the control group were lower than those in the combined group(P<0.05).The total adverse reaction rate in the control group was 23.91%(11/46),which was not statistically significant compared with 28.26%(13/46)in the combined group(P>0.05).Conclusion Qufeng Daotan Decoctionbased on the theory that"all diseases are caused by phlegm"has a significant clinical effect on patients with secondary generalized tonic clonic seizures,which can improve cognitive function and improve the quality of life.

关 键 词：“百病皆为痰作祟”理论 祛风导痰汤 电子生物反馈技术 续发性全身强直-阵挛性发作癫痫 

分 类 号：R742.1[医药卫生—神经病学与精神病学]