基于多巴胺系统调节的治疗抽动障碍中药作用探讨  

Effect of Traditional Chinese Medicine on Tic Disorder Based on Dopamine System Regulation

作　　者：陈慧敏 史文丽[1] 贺晴 马丙祥[1] CHEN Huimin;SHI Wenli;HE Qing;MA Bingxiang(Henan University of Chinese Medicine,Zhengzhou 450000,Henan,China)

机构地区：[1]河南中医药大学,河南郑州450000

出　　处：《辽宁中医杂志》2023年第3期204-206,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金青年科学基金项目(8190152112);河南省中管局项目(2019ZY2116)。

摘　　要：近年来,抽动障碍(TD)的患病率逐年增加,虽不危及生命,但已成为危害儿童身心健康的常见严重慢性疾病之一,对家庭和社会也有着不同程度的影响。TD作为一种神经发育障碍性疾病,其发病因素及发病机制尚不清晰,但中医药在治疗TD中的临床疗效确切,而从多巴胺系统对TD作用机制的研究逐渐深入,文章从中药调控多巴胺系统对TD的影响出发进行综述。In recent years, the prevalence of tic disorder(TD) is increasing year by year.Although TD is not life-threatening, it has become one of the common serious chronic diseases that harm children′s physical and mental health, and has varying degrees of impact on families and society.TD is a neurodevelopmental disorder and its pathogenesis and pathogenesis are not clear, but the clinical efficacy of traditional Chinese medicine in the treatment of TD is definite, and the research on the mechanism of dopamine system on TD is gradually in-depth.This paper reviewed the effects of traditional Chinese medicine on TD regulation of dopamine system.

关 键 词：中药 抽动障碍 多巴胺受体 多巴胺转运体 儿茶酚胺氧位甲基转移酶 单胺氧化酶 

分 类 号：R749[医药卫生—神经病学与精神病学]