郑州地区缺血性心脑血管病患者二级预防用药现状及用药依从性调查  

Status and compliance of secondary prophylactic medication in patients with ischemic cardiocerebrovascular disease in Zhengzhou

作　　者：徐磊[1] 周美玲 申晓丽 XU Lei;ZHOU Mei-ling;SHEN Xiao-li(Zhengzhou Second Hospital,Zhengzhou 450000,China)

机构地区：[1]郑州市第二人民医院,河南郑州450000

出　　处：《华南预防医学》2023年第1期27-31,共5页South China Journal of Preventive Medicine

摘　　要：目的 探讨缺血性心脑血管病患者二级预防用药现状,并对影响其用药依从性的相关因素进行分析。方法 纳入2021年1月至2022年1月于郑州市某医院接受治疗的缺血性心脑血管病患者作为研究对象,对该人群进行二级预防用药情况的问卷调查,采用描述性分析方法对用药类型及用药依从性等结果进行分析,并采用单、多因素分析方法对该人群二级预防用药依从性的影响因素进行分析。结果 本研究共对763例缺血性心脑血管病患者进行调查,有效调查患者750例,有效率为98.29%。其中缺血性心脏病患者306例,缺血性脑卒中患者422例,22例患者合并缺血性心脏病及缺血性脑卒中。750例缺血性心脑血管病患者中198例患者自报服用抗血小板药或他汀类药物,占比为26.40%,仅服用抗血小板类药物和仅服用他汀类药物的患者占比分别为45.95%(91/198)、29.29%(58/198)。112例患者依从性较好,服药依从率为56.57%。二分类Logistic回归分析结果显示性别(OR=2.289)、年龄(OR=0.624)、文化程度(OR=2.020)、工作情况(OR=3.391)、家庭年收入(OR=1.723、2.164)、合并高血压(OR=1.266)和病程(OR=0.531、0.267)均是影响缺血性心脑血管病患者二级预防用药依从性相关因素。结论郑州地区缺血性心脑血管病患者二级预防用药率较低,服药依从性不佳,其中患者的性别、年龄、文化程度、家庭年收入、工作情况及病程等均是影响其服药依从性的重要因素。ObjectiveTo explore the status of secondary prophylactic medication in patients with ischemic cardi-ocerebrovascular disease,and to analyze the related factors affecting medication compliance.MethodsPatients with ischemic cardiocerebrovascular disease who received treatment in a hospital in Zhengzhou from January 2021 to January 2022 were included to conduct a questionnaire survey on secondary prophylactic medication,and results of medication type and compliance were analyzed by descriptive analysis method.The factors influencing the compliance of secondary prophylactic medication in this population were analyzed by univariate and multivariate analysis methods.ResultsA total of 763 patients with ischemic cardiocerebrovascular disease were investigated in this study,and 750 patients were effec-tively investigated,the effective rate was 98.29%.Among them,306 patients with ischemic heart disease,422 patients with ischemic stroke,and 22 patients complicated with ischemic heart disease and ischemic stroke.Of the 750 patients with ischemic cardiocerebrovascular disease,198 cases reported taking antiplatelet drugs or statins,accounting for 26.40%.The proportion of patients taking antiplatelet drugs only and statins only was 45.95%(91/198)and 29.29%(58/198),respec-tively.There were 112 patients with good medication compliance,and the compliance rate was 56.57%.Binary Logistic re-gression analysis showed that gender(OR=2.289),age(OR=0.624),an education level(OR=2.020),work status(OR=3.391),annual family income(OR=1.723,2.164),complicated with hypertension(OR=1.266),and course of disease(OR=0.531,0.267)were related factors affecting compliance of secondary prophylactic medication in patients with ischemic cardiocerebrovascular disease.ConclusionsThe rate of secondary prophylaxis medication was low in pa-tients with ischemic cardiocerebrovascular disease in Zhengzhou,and the compliance was poor,among which the gender,age,education level,annual family income,work status,and course of disease were all important factors affect

关 键 词：缺血性心脑血管病 缺血性脑卒中 缺血性心脏病 二级预防 服药依从性 

分 类 号：R743.3[医药卫生—神经病学与精神病学]