自膨式金属支架在肝硬化食管静脉曲张出血中的应用进展  

Progress in the application of self-expanding metallic stents in patients with esophageal variceal bleeding in cirrhosis

作　　者：杨威(综述) 宣佶(审校) YANG Wei;XUAN Ji(Department of Gastroenterology,Jinling School of Clinical Medicine,Nanjing Medical University/General Hospital of Eastern Theater Command,PLA,Nanjing 210002,Jiangsu,China)

机构地区：[1]南京医科大学金陵临床医学院(东部战区总医院)消化内科,南京210002

出　　处：《医学研究与战创伤救治》2023年第1期80-85,共6页Journal of Medical Research & Combat Trauma Care

基　　金：江苏省卫生健康委医学科研项目(H2019073);江苏省“333高层次人才”培养工程项目(BRA2018408);江苏省老年健康科研项目(LKM2022030)。

摘　　要：食管静脉曲张出血(EVB)是肝硬化患者最严重和最常见的并发症之一,目前一线疗法包括内镜下套扎术、组织胶或硬化剂注射等,止血效果得到广泛认可,但仍有部分患者效果不佳,称为难治性静脉曲张出血患者。近年来,多家机构尝试使用自膨式食管金属支架(SEMS)治疗肝硬化食管静脉曲张出血,其安全性和有效性均已得到初步验证,在临床上有着独特的应用前景。文章主要就支架置入治疗肝硬化食管静脉曲张出血的应用现状与研究方向进行综述。Esophageal variceal bleeding(EVB)is one of the most serious and common complications in patients with cirrhosis.Currently,first-line therapies including endoscopic ligation,tissue glue or sclerotherapy have been widely recognized for their hemostatic effect,but there are still some patients with poor results,known as refractory variceal bleeding.In recent years,many institutions have tried to use self-expanding esophageal metallic stents(SEMS)for the treatment of esophageal variceal bleeding in cirrhosis.Its safety and efficacy have been preliminarily verified,and it has a unique application prospect in clinical practice.This article mainly reviews the application status and research direction of stent implantation in the treatment of esophageal variceal bleeding in cirrhosis.

关 键 词：食管支架 肝硬化 食管静脉曲张 静脉曲张出血 经颈静脉肝内门体分流术 

分 类 号：R575.2[医药卫生—消化系统]