Quality Standard of Qiang Herb Sophora davidii var.chuansiensis  

作　　者：Mingkang FENG Qubiejunzhang Qubieaxiang Dongmei SHA Wenbing LI Yuan LIU 

机构地区：[1]College of Pharmacy,Southwest Minzu University,Chengdu 610041,China [2]Sichuan Provincial Qiang-Yi Medicinal Resources Protection and Utilization Technology Engineering Laboratory,Chengdu 610225,China [3]National Ethnic Affairs Commission Key Laboratory for Protection and Utilization of Qinghai-Tibet Plateau Ethnic Medicinal Resources,Chengdu 610225,China [4]Institute of Qinghai-Tibet Plateau,Southwest Minzu University,Chengdu 610041,China

出　　处：《Medicinal Plant》2023年第1期33-36,40,共5页药用植物：英文版

基　　金：Supported by National Key R&D Plan(2018YFC1708005);Sichuan Science and Technology Plan Project(2021YFS0043);Improvement of the Standard of Traditional Chinese Medicine(Ethnic Medicine)of Sichuan Medical Products Administration(510201202102305);Leading Talent Support Plan in 2021;Research Projects of Special Funds for Basic Scientific Research Business Expenses of Central Colleges and Universities(2021PTJS35).

摘　　要：[Objectives]To establish the quality standard of common clinical folk herb Sophora davidii var.chuansiensis.[Methods]The qualitative identification was performed by microscopic method and thin-layer chromatography(TLC).The contents of moisture,total ash,acid insoluble ash and extract were determined according to the methods of the Chinese Pharmacopoeia(2020).High performance liquid chromatography(HPLC)was used to determine the contents of oxymatrine and oxysophocarpine.[Results]The microscopic characteristics were obvious,including crystal sheath fiber,calcium oxalate square crystal,non glandular hair,stone cells,epidermal cells,stomata,cork cells,vessels with marginal pits and so on.TLC spots were clear,and the resolution was good.The contents of moisture,total ash,acid insoluble ash and extract from 10 batches of samples were 4.70%-8.33%,3.43%-4.19%,0.65%-1.02%and 14.67%-22.04%respectively.The determination results of oxymatrine were between 0.10%-0.33%,with an average value of 0.19%.The determination results of sophocarpine oxide were between 0.30%-0.38%,with an average value of 0.34%.[Conclusions]The established quality standard of S.davidii var.chuansiensis had good specificity and accuracy,and could be used for the quality control of herb S.davidii var.chuansiensis.

关 键 词：Qiang herbs Sophora davidii var.chuansiensis OXYMATRINE Sophocarpine oxide HPLC Quality standard 

分 类 号：R29[医药卫生—民族医学]