OXYMATRINE

作品数:70被引量:467H指数:14
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相关领域:医药卫生更多>>
相关作者:王国俊向晓星李玉莉蔡雄袁海龙更多>>
相关机构:第二军医大学解放军302医院解放军第302医院汇仁集团更多>>
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Network pharmacology-based exploration of pathways involved in the inhibition of hepatocellular carcinoma cell proliferation by Oxymatrine
《Cancer Advances》2024年第11期1-8,共8页Jin-Feng Yao Shuang-Quan Wang 
Objective:To explore the effect of Oxymatrine(OMT)on hepatocellular carcinoma cells and its possible action pathways.Methods:The core targets of Oxymatrine action in hepatocellular carcinoma were identified using netw...
关键词:hepatocellular carcinoma network pharmacology OXYMATRINE 
Simultaneous Determination of Trace Matrine and Oxymatrine Pesticide Residues in Tea by Magnetic Solid-Phase Extraction Coupled with Liquid Chromatography-Tandem Mass Spectrometry
《Journal of Analysis and Testing》2024年第2期245-250,共6页Hongmei Liu Yang Li Yangjiayi Xiang Hao Cao Yan Li 
supported by funds provided by the National Natural Science Foundation of China(21974024 and 22274025)。
We developed a magnetic solid-phase extraction method using Fe_(3)O_(4)@polydopamine(Fe_(3)O_(4)@PDA)as adsorbents,coupled with liquid chromatography-tandem mass spectrometry(LC-MS/MS),for the enrichment and quantific...
关键词:ADSORBENT CHROMATOGRAPHY adsorption 
Quality Standard of Qiang Herb Sophora davidii var.chuansiensis
《Medicinal Plant》2023年第1期33-36,40,共5页Mingkang FENG Qubiejunzhang Qubieaxiang Dongmei SHA Wenbing LI Yuan LIU 
Supported by National Key R&D Plan(2018YFC1708005);Sichuan Science and Technology Plan Project(2021YFS0043);Improvement of the Standard of Traditional Chinese Medicine(Ethnic Medicine)of Sichuan Medical Products Administration(510201202102305);Leading Talent Support Plan in 2021;Research Projects of Special Funds for Basic Scientific Research Business Expenses of Central Colleges and Universities(2021PTJS35).
[Objectives]To establish the quality standard of common clinical folk herb Sophora davidii var.chuansiensis.[Methods]The qualitative identification was performed by microscopic method and thin-layer chromatography(TLC...
关键词:Qiang herbs Sophora davidii var.chuansiensis OXYMATRINE Sophocarpine oxide HPLC Quality standard 
Matrine, oxymatrine, and compound Kushen injection from the roots of Sophora flavescens: an overview of their anticancer activities被引量:1
《Journal of Chinese Pharmaceutical Sciences》2022年第5期321-333,共13页Eric Wei Chiang Chan Siu Kuin Wong Hung Tuck Chan 
In the present review,we updated current information on the chemistry,contents,and anticancer properties of matrine(MT),oxymatrine(OMT),and compound Kushen injection(CKI).The anticancer properties were focused on lung...
关键词:INJECTION INVASION ROOTS 
Study on possible synergistic anticancer cachexia effects of the main active compounds of Radix Sophorae flavescentis
《Traditional Medicine Research》2021年第4期46-61,共16页Hong Zhang Lin-Lin Chen Meng-Yi Chi Xi-Peng Sun Quan-Jun Yang Li-Li Wan Cheng Guo 
the National Natural Science Foundation of China(No.81873042,81872494 and 81803633).
Background:Cancer cachexia is a complex disease secondary to cancer,and no specific therapy for it has been found.The Chinese herb Kushen(Radix Sophorae flavescentis)is the dried root of Sophora flavescens Aiton,which...
关键词:Radix Sophorae flavescentisn Cancer cachexia Kurarinol MATRINE OXYMATRINE TNF signaling pathway 
Preparation and Evaluation of MPEG-PCL Polymeric Nanoparticles Against Gastric Cancer被引量:1
《Journal of Wuhan University of Technology(Materials Science)》2020年第6期1162-1168,共7页LIU Xia LI Juncan HUANG Long YANG Jin WANG Yaowen YANG Mengjia TANG Mingxiu QIU Tong 
Funded by the National Natural Science Foundation of China(No.51273156);the Health Commission of Hubei Province Scientific Research Project(No.WJ2019H275)。
This paper provides a new treatment for gastric cancer with a new OMT delivery system.We synthesized MPEG-PCL,an amphiphilic polymer,to construct a nanoparticle encapsulated OMT by pH gradient method,and then examined...
关键词:MPEG-PCL NANOPARTICLES OXYMATRINE gastric cancer 
Correction to: Oxymatrine Inhibits Bocavirus MVC Replication, Reduces Viral Gene Expression and Decreases Apoptosis Induced by Viral Infection被引量:1
《Virologica Sinica》2019年第6期729-729,共1页Yanqin Ding Na Li Jinhan Sun Linran Zhang Jianhui Guo Xueqi Hao Yuning Sun 
In the original version of Fig.2,the marker line between column 2 and column 6 is redundant(Fig.2A),and MVC label and MVCIOMT label were accidentally swapped(Fig.2B).The correct Fig.2 is provided below.
关键词:MVC REPLICATION SWAP 
Oxymatrine Inhibits Bocavirus MVC Replication, Reduces Viral Gene Expression and Decreases Apoptosis Induced by Viral Infection被引量:2
《Virologica Sinica》2019年第1期78-87,共10页Yanqin Ding Na Li Jinhan Sun Linran Zhang Jianhui Guo Xueqi Hao Yuning Sun 
funded by the Natural Sciences Foundation of China (31760041) to YS;the West China first-class Disciplines Basic Medical Sciences at Ningxia Medical University (No. NXYLXK2017B07);Innovative Training Program for College Students (201510752010) to NL
Oxymatrine(OMT), as the main active component of Sophoraflavescens, exhibits a variety of pharmacological properties,including anti-oxidative, anti-inflammatory, anti-tumor, and anti-viral activities, and currently is...
关键词:OXYMATRINE (OMT) Minute virus of CANINES (MVC) Infection REPLICATION APOPTOSIS 
Effects and Mechanism of Oxymatrine on Proliferation,Invasion and Migration of Hepatocellular Carcinoma Cells
《Medicinal Plant》2018年第6期72-75,88,共5页Tongyuan DENG Guiliu HUANG Zansong HUANG Xihan ZHOU Gaoyu HU Yueqiu QIN 
Supported by Natural Science Foundation Project of Guangxi(2014GXNSFAA118143);Excellent Talents Funding Program of Colleges and Universities in Guangxi(RC20077029);Key Scientific Research Program for Medical Care and Health of Guangxi Health Department(200887)
[Objectives] To observe the effects of oxymatrine on the proliferation,invasion and migration of hepatocellular carcinoma cells,and to explore its possible molecular mechanism.[Methods]The hepatocellular carcinoma cel...
关键词:HEPATOCELLULAR carcinoma OXYMATRINE Cell PROLIFERATION TUMOR INVASION TUMOR metastasis CADHERIN CD44 
Inhibitory effect of oxymatrine on hepatocyte apoptosis via TLR4/PI3K/Akt/GSK-3β signaling pathway被引量:13
《World Journal of Gastroenterology》2017年第21期3839-3849,共11页Xian Zhang Wei Jiang Ai-Ling Zhou Min Zhao Dao-Rong Jiang 
Supported by the Jiangsu Bureau of Traditional Chinese Medicine,No.YB2015177
To evaluate the effect of oxymatrine (OMT) on hepatocyte apoptosis in rats with lipopolysaccharide (LPS)/D-galactosamine (D-GalN)-induced acute liver failure (ALF).METHODSLPS/D-GalN was used to establish a model of AL...
关键词:OXYMATRINE Acute liver failure Toll-like receptor 4 APOPTOSIS 
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