CADHERIN

作品数:333被引量:854H指数:12
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相关领域:医药卫生更多>>
相关作者:黄志勇陈孝平王恩华张自森赵瑞力更多>>
相关机构:中国医科大学华中科技大学郑州大学南方医科大学更多>>
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相关基金:国家自然科学基金国家教育部博士点基金河南省医学科技攻关计划项目国家重点基础研究发展计划更多>>
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Cadherin-18 loss in prospermatogonia and spermatogonial stem cells enhances cell adhesion through a compensatory mechanism
《Zoological Research》2024年第5期1048-1060,共13页Xiao-Xiao Li Dan-Chen Zhang Yan Wang Jian Wen Xing-Ju Wang Yu-Lu Cao Ru Jiang Jia-Rui Li Yi-Nuo Li He-He Liu Wen-Hai Xie Zheng-Feng Xu Ping Hu Kang Zou 
supported by the Jiangsu Seed Industry Revitalization Project(JBGS[2021]024);Fundamental Research Funds for the Central Universities(KYT2023002);Jiangsu Province Capability Improvement Project through Science,Technology;Education Jiangsu Provincial Medical Key Discipline(ZDXK202211);Shandong Province Natural Science Foundation(ZR2020MC074)
Extracellular membrane proteins are crucial for mediating cell attachment,recognition,and signal transduction in the testicular microenvironment,particularly germline stem cells.Cadherin 18(CDH18),a type Ⅱ classical ...
关键词:Extracellular signal FERTILITY Quiescency Wnt signaling pathway 
血府逐瘀汤对气虚血瘀型慢性心力衰竭患者心肌保护及Cadherin-NrF2通路铁死亡交互作用的影响
《中国基层医药》2024年第7期1006-1012,共7页吴费凯 肖美霞 施胜铭 
浙江省湖州市科学技术局公益性应用研究(2021GYB44)。
目的观察血府逐瘀汤对气虚血瘀型慢性心力衰竭患者心肌保护及Cadherin-NrF2通路铁死亡交互作用的影响。方法选择2021年2月至2022年5月湖州市第一人民医院治疗的气虚血瘀型心力衰竭患者100例进行病例对照研究, 分组方式为随机数字表法。5...
关键词:心力衰竭  黏蛋白类 氧化性应激 内皮细胞 疗效比较研究 血府逐瘀汤 
Cadherin 17在胃癌中的表达与临床意义
《浙江临床医学》2024年第5期749-751,共3页李自宁 马海芬 
宁波市医学科技计划项目(2017A33)。
目的探讨钙粘蛋白17(CDH17)在胃癌中表达意义及与其它部位腺癌的鉴别价值。方法选取2018年7月至2023年6月本院收治的消化系统来源原发性腺癌348例,包括胃癌114例,结直肠癌150例,胰胆管癌55例以及非消化系统来源的原发性腺癌29例。检测CD...
关键词:钙粘蛋白17 尾型同源盒转录因子-2 胃癌 腺癌 
Functional assessment of cadherin as a shared mechanism for cross/dual resistance to Cry1Ac and Cry2Ab in Helicoverpa zea
《Journal of Integrative Agriculture》2024年第5期1604-1617,共14页Jizhen Wei Min Zhang Pin Li Zhongyuan Deng Xinming Yin Shiheng An Xianchun Li 
funded by the USDA National Institute of Food and Agriculture (Hatch Grant ARZT-1360890-H31-164 and multi-state grant ARZ-T1370680-R31-172 (NC246));the National Natural Science Foundation of China (NSFC)–Henan Joint Major Grant (U2004206);the State Key Laboratory of Cotton Biology Open Fund, Zhengzhou University, China (CB2020A06);the Henan Agriculture Research System, China (HARS22-09-G3);the earmarked fund for China Agriculture Research System (CARS-27)
Helicoverpa zea is a major target pest of pyramided transgenic crops expressing Cry1,Cry2 and/or Vip3Aa proteins from Bacillus thuringiensis(Bt)in the United States.Laboratory-selected Cry1Ac/Cry2Ab cross resistance a...
关键词:Bt crops CADHERIN Cry toxin RECEPTOR resistance mechanism 
Dynamics and functions of E‑cadherin complexes in epithelial cell and tissue morphogenesis被引量:4
《Marine Life Science & Technology》2023年第4期585-601,共17页Na Zhang Matthias Häring Fred Wolf Jörg Großhans Deqing Kong 
supported by the grants of the Deutsche Forschungsgemeinschaft(GR1945/10-1and GR1945/10-2 to JG)。
Cell–cell adhesion is at the center of structure and dynamics of epithelial tissue.E-cadherin–catenin complexes mediate Ca^(2+)-dependent trans-homodimerization and constitute the kernel of adherens junctions.Beyond...
关键词:Nanoscale architectures PHOSPHORYLATION GLYCOSYLATION Computational modelling 
LincRNA-P21 knockdown facilitates esophageal squamous cell carcinoma cell progression by upregulating cadherin 5 via YTH domain containing 1
《Acta Biochimica et Biophysica Sinica》2023年第11期1797-1805,共9页Jianjun Wang Li Zhu Quan Zhang Tian Xia Wenjian Yao Li Wei 
supported by the grants from the Key Science and Technology Projects in Henan Province (Nos.202102310457 and 212102310669);the Henan Province Medical Science and Technology Research Plan Joint Construction Project (No.LHGJ20200034);the“23456 Talent Project”of Henan Provincial People’s Hospital.
LincRNA-P21 is a tumor suppressor in esophageal squamous cell carcinoma(ESCC).Cell adhesion modules play vital roles in cell-cell and cell-extracellular matrix(ECM)interactions and malignant cancer progression.In this...
关键词:lincRNA-P21 esophageal squamous cell carcinoma YTHDC1 CDH5 
A computational study for understanding the impact of p120-catenin on the cis-dimerization of cadherin
《Journal of Molecular Cell Biology》2023年第9期14-24,共11页Zhaoqian Su Vinh H.Vu Deborah ELeckband Yinghao Wu 
supported by the National Institutes of Health under grant number 1R01GM117104;supported by the National Institutes of Health under grant numbers R01GM120238 and R01GM122804;supported by a start-up grant from Albert Einstein College of Medicine.Computational support was provided by Albert Einstein College of Medicine High Performance Computing Center and by the National Science Foundation through the Extreme Science and Engineering Discovery Environment(XSEDE)undergrant numberTG-MCB200014.
A prototype of cross-membrane signal transduction is that extracellular binding of cell surface receptors to their ligands induces intracellular signalling cascades.However,much less is known about the process in the ...
关键词:multiscale modeling inside-out signaling molecular dynamics simulations cadherin-mediated cell adhesion 
当归芍药散对糖尿病肾损伤大鼠肾小管上皮细胞转分化的影响被引量:2
《中国老年学杂志》2023年第18期4453-4456,共4页刘岳轩 陈文钰 陈言 马梦舸 王鹏禹 刘湘花 高小玲 金艳 刘晨 吴效通 王晓 李晓冰 
国家自然科学基金(81603527);河南省科技攻关计划项目(162102310466)。
目的观察当归芍药散对糖尿病肾损伤模型大鼠的干预作用。方法70只SD大鼠随机选取8只作为正常组,其余大鼠采用高糖高脂饲料喂养联合链脲佐菌素腹腔注射诱导糖尿病大鼠模型,造模成功后随机分为模型组、雷公藤多苷组(6 mg/kg)、当归芍药散...
关键词:当归芍药散 E-钙黏蛋白(cadherin) α-平滑肌肌动蛋白(SMA) 波形蛋白(Vimentin) 
N‑Cadherin‑Functionalized Nanofiber Hydrogel Facilitates Spinal Cord Injury Repair by Building a Favorable Niche for Neural Stem Cells被引量:2
《Advanced Fiber Materials》2023年第4期1349-1366,共18页Kaiyuan Yang Jia Yang Weitao Man Zhe Meng Chun‑Yi Yang Zheng Cao Jun Liu Kunkoo Kim Yaosai Liu Shuhui Yang Yi Guo Zhijun He Chao Ma Guihuai Wang Xiumei Wang 
National Natural Science Foundation of China(Grant Nos.32271414 and 82201521);Tsinghua Precision Medicine Foundation(Grant No.2022TS001);National Key Research and Development Program of China(Grant No.2020YFC1107600).
The inhospitable niche at the injury site after spinal cord injury(SCI)brings several challenges to neural stem cell(NSC)therapy,such as limited NSC retention and neuronal differentiation.Biomaterial-based stem cell t...
关键词:N-CADHERIN Aligned fibrin nanofiber scaffold NICHE Neural stem cell Spinal cord injury 
Inhibition of Foxp4 Disrupts Cadherin-based Adhesion of Radial Glial Cells,Leading to Abnormal Differentiation and Migration of Cortical Neurons in Mice
《Neuroscience Bulletin》2023年第7期1131-1145,共15页Xue Li Shimin Zou Xiaomeng Tu Shishuai Hao Tian Jiang Jie-Guang Chen 
supported by the Wenzhou Municipal Science and Technology Bureau(Y20210901);the Natural Science Foundation of Zhejiang Province(LQ20H090001);the Scientific Research Fund of Wenling Science and Technology Bureau(2018C320001).
Heterozygous loss-of-function variants of FOXP4 are associated with neurodevelopmental disorders(NDDs)that exhibit delayed speech development,intellectual disability,and congenital abnormalities.The etiology of NDDs i...
关键词:NEUROGENESIS Radial migration Radial glial cell Ventricular zone N-CADHERIN 
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