supported by the Jiangsu Seed Industry Revitalization Project(JBGS[2021]024);Fundamental Research Funds for the Central Universities(KYT2023002);Jiangsu Province Capability Improvement Project through Science,Technology;Education Jiangsu Provincial Medical Key Discipline(ZDXK202211);Shandong Province Natural Science Foundation(ZR2020MC074)
Extracellular membrane proteins are crucial for mediating cell attachment,recognition,and signal transduction in the testicular microenvironment,particularly germline stem cells.Cadherin 18(CDH18),a type Ⅱ classical ...
funded by the USDA National Institute of Food and Agriculture (Hatch Grant ARZT-1360890-H31-164 and multi-state grant ARZ-T1370680-R31-172 (NC246));the National Natural Science Foundation of China (NSFC)–Henan Joint Major Grant (U2004206);the State Key Laboratory of Cotton Biology Open Fund, Zhengzhou University, China (CB2020A06);the Henan Agriculture Research System, China (HARS22-09-G3);the earmarked fund for China Agriculture Research System (CARS-27)
Helicoverpa zea is a major target pest of pyramided transgenic crops expressing Cry1,Cry2 and/or Vip3Aa proteins from Bacillus thuringiensis(Bt)in the United States.Laboratory-selected Cry1Ac/Cry2Ab cross resistance a...
supported by the grants of the Deutsche Forschungsgemeinschaft(GR1945/10-1and GR1945/10-2 to JG)。
Cell–cell adhesion is at the center of structure and dynamics of epithelial tissue.E-cadherin–catenin complexes mediate Ca^(2+)-dependent trans-homodimerization and constitute the kernel of adherens junctions.Beyond...
supported by the grants from the Key Science and Technology Projects in Henan Province (Nos.202102310457 and 212102310669);the Henan Province Medical Science and Technology Research Plan Joint Construction Project (No.LHGJ20200034);the“23456 Talent Project”of Henan Provincial People’s Hospital.
LincRNA-P21 is a tumor suppressor in esophageal squamous cell carcinoma(ESCC).Cell adhesion modules play vital roles in cell-cell and cell-extracellular matrix(ECM)interactions and malignant cancer progression.In this...
supported by the National Institutes of Health under grant number 1R01GM117104;supported by the National Institutes of Health under grant numbers R01GM120238 and R01GM122804;supported by a start-up grant from Albert Einstein College of Medicine.Computational support was provided by Albert Einstein College of Medicine High Performance Computing Center and by the National Science Foundation through the Extreme Science and Engineering Discovery Environment(XSEDE)undergrant numberTG-MCB200014.
A prototype of cross-membrane signal transduction is that extracellular binding of cell surface receptors to their ligands induces intracellular signalling cascades.However,much less is known about the process in the ...
National Natural Science Foundation of China(Grant Nos.32271414 and 82201521);Tsinghua Precision Medicine Foundation(Grant No.2022TS001);National Key Research and Development Program of China(Grant No.2020YFC1107600).
The inhospitable niche at the injury site after spinal cord injury(SCI)brings several challenges to neural stem cell(NSC)therapy,such as limited NSC retention and neuronal differentiation.Biomaterial-based stem cell t...
supported by the Wenzhou Municipal Science and Technology Bureau(Y20210901);the Natural Science Foundation of Zhejiang Province(LQ20H090001);the Scientific Research Fund of Wenling Science and Technology Bureau(2018C320001).
Heterozygous loss-of-function variants of FOXP4 are associated with neurodevelopmental disorders(NDDs)that exhibit delayed speech development,intellectual disability,and congenital abnormalities.The etiology of NDDs i...