三种肝叶增生技术的研究进展  

Research progress of three techniques for hepatic hyperplasia

作　　者：许豪杰 徐嘉泽 胡智明 杨鸿国 Xu Haojie;Xu Jiaze;Hu Zhiming;Yang Hongguo(The Second Clinical Medical College of Zhejiang Chinese Medical University,Hangzhou 310051,China;Department of Hepatobiliary and Pancreatic Surgery,Tongde Hospital of Zhejiang Province,Hangzhou 310012,China)

机构地区：[1]浙江中医药大学第二临床医学院,杭州310051 [2]浙江省立同德医院肝胆胰外科,杭州310012

出　　处：《中华肝胆外科杂志》2023年第3期227-230,共4页Chinese Journal of Hepatobiliary Surgery

摘　　要：外科手术切除是肝癌患者获得长期生存的重要手段之一。然而大部分肝癌患者确诊时已为中晚期,失去手术治疗的机会。针对这部分失去手术机会的患者,有外科医生提出了计划性肝切除的理念即有计划地降低肿瘤分期、增加剩余肝体积(FLR),从而达到提高手术安全性,延长患者生存期的目的。对于前期评估或/和治疗后FLR不足的患者,肝叶增生是计划性肝切除的重要环节,通过各种手段在较短的时间内有效增加FLR。门静脉结扎术和门静脉栓塞术、联合肝脏离断和门静脉结扎的二步肝切除术、肝静脉剥夺术是三种主要的肝叶增生技术。本文针对这三种肝叶增生技术进行综述。Surgical resection is one of the important means to achieve long-term survival for patients with liver malignant tumor.However,most of the liver malignant tumor has been diagnosed in the middle and late stage,and lose the chance of surgical treatment.For these patients who have lost the chance of surgery,some surgeons have proposed the concept of planned liver resection,which is to reduce tumor stage and increase future liver remnant(FLR)in a planned way,so as to improve the safety of surgery and prolong the survival time of patients after surgery.For patients with FLR insufficiency after prior evaluation or/and treatment,the technique of hepatic hyperplasia is an important part of planned hepatectomy,that is,to effectively increase FLR in a short period of time by various means.Portal vein ligation(PVL)and portal vein embolization(PVE),associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)and liver venous deprivation(LVD)are three main techniques for hepatic hyperplasia.This article reviews the principle,effect and safety of three liver augmentation techniques.

关 键 词：肝切除术 门静脉栓塞术 联合肝脏离断和门静脉结扎的二步肝切除术 肝静脉剥夺术 

分 类 号：R735.7[医药卫生—肿瘤]