低温等离子射频消融术与CO_(2)激光微创手术治疗喉癌患者对VHI及预后的影响  

Effects of low-temperature plasma radiofrequency ablation and CO_(2) laser minimally invasivesurgery on the VHI and prognosis in patients with laryngeal cancer

作　　者：李念胜 王晓华 王淑婷 张俊萍 李程远 Li Niansheng;Wang Xiaohua;Wang Shuting;Zhang Junping;Li Chengyuan(Department of Otolaryngology,Weihai Central Hospital,Weihai 264400,China)

机构地区：[1]威海市中心医院耳鼻咽喉科,威海264400

出　　处：《国际医药卫生导报》2023年第7期932-935,共4页International Medicine and Health Guidance News

基　　金：山东省医药卫生科技发展计划项目(2019WS604)。

摘　　要：目的探讨低温等离子射频消融术与CO_(2)激光微创手术治疗喉癌患者对术后嗓音障碍指数(voice handicap index,VHI)及预后的影响。方法选取2017年6月至2021年6月威海市中心医院收治的86例喉癌患者,分为研究组(采用低温等离子射频消融术治疗)和对照组(采用CO_(2)激光微创手术治疗)。对照组男29例,女14例,年龄43~80(59.78±9.47)岁;研究组男27例,女16例,年龄39~79(58.85±8.99)岁。对比两组患者术中出血量、手术时间、术后VHI、术后1个月黏膜恢复情况以及术后复发率。采用t检验、χ^(2)检验。结果与对照组相比,研究组术中出血量少(t=8.205,P<0.001),手术时间较短(t=5.839,P<0.001)。术后1个月两组患者嗓音功能VHI评分均降低,且研究组低于对照组[(4.25±0.57)分比(6.85±1.04)分](t=14.376,P<0.001)。两组患者术后复发率对比,研究组低于对照组[4.65%(2/43)比20.93%(9/43)],差异有统计学意义(χ^(2)=5.108,P=0.024)。研究组术后1个月黏膜恢复情况优于对照组(χ^(2)=4.074,P=0.044)。结论低温等离子射频消融术治疗喉癌患者手术用时短,出血量少,改善患者的嗓音,改善患者预后,值得推广。Objective To investigate the effects of low-temperature plasma radiofrequency ablation and CO_(2) laser minimally invasive surgery on postoperative voice handicap index(VHI)and prognosis in patients with laryngeal cancer.Methods A total of 86 cases of laryngeal cancer admitted to Weihai Central Hospital from June 2017 to June 2021 were retrospectively selected and were divided into a study group treated by low-temperature plasma radiofrequency ablation and a control group treated by CO_(2) laser minimally invasive surgery.In the control group,there were 29 males and 14 females,aged 43-80(59.78±9.47)years;in the study group,there were 27 males and 16 females,aged 39-79(58.85±8.99)years.The intraoperative blood loss,operative time,postoperative VHI score,mucosal recovery 1 month after surgery,and postoperative recurrence rate were compared between the two groups.t test andχ^(2)test were used.Results Compared with those in the control group,the study group had less intraoperative blood loss(t=8.205,P<0.001)and shorter operation time(t=5.839,P<0.001).The VHI scores of voice function in both groups were decreased 1 month after surgery,and the VHI score in the study group was lower than that in the control group[(4.25±0.57)points vs.(6.85±1.04)points](t=14.376,P<0.001).The postoperative recurrence rate in the study group was lower than that in the control group[4.65%(2/43)vs.20.93%(9/43)],with a statistically significant difference(χ^(2)=5.108,P=0.024).The mucosal recovery of the study group was better than that of the control group 1 month after surgery(χ^(2)=4.074,P=0.044).Conclusion Low temperature plasma radiofrequency ablation in the treatment of laryngeal cancer has short operation time and less blood loss,and can improve the patients'voice and prognosis,which is worth promoting.

关 键 词：低温等离子射频消融术 CO_(2)激光微创手术 喉癌 嗓音功能 

分 类 号：R739.65[医药卫生—肿瘤]