颅骨硬化性上皮样纤维肉瘤1例报告并文献复习  

Sclerosing epithelioid fibrosarcoma of the skull(a case report and literature review)

作　　者：赵春瑞 隋建美 董世祥 叶浩 王颖[3] 杨明 李泽浩 韩锋 ZHAO Chun-rui;SUI Jian-mei;DONG Shi-xiang(Department of Surgery,School of Clinical Medicine,Guizhou Medical University,Guiyang 550025,Guizhou,China)

机构地区：[1]贵州医科大学临床医学院,贵阳550025 [2]贵州医科大学附属医院神经外科,贵阳550025 [3]贵州省肿瘤医院外科

出　　处：《临床神经外科杂志》2023年第2期208-211,共4页Journal of Clinical Neurosurgery

基　　金：贵州省科技计划项目(黔科合LH字[2017]7213号)。

摘　　要：目的 探讨硬化性上皮样纤维肉瘤(SEF)的临床特点、影像学表现、病理诊断及治疗方法。方法 回顾分析1例颅骨SEF患者的临床资料,并复习相关文献。结果 本例男性患者,40岁,临床表现为头部持续增大包块;头颅CT检查示,左侧顶骨近椭圆形溶骨性病变。行手术切除,术中见肿瘤位于左侧顶枕部,固定于颅骨深面,边界尚清,质韧,向下生长压迫脑组织,相邻硬脑膜有增厚,手术全切病灶和受累硬脑膜。术后病理检查诊断为硬化性上皮样纤维肉瘤。术后随访15个月未见病灶复发。结论 颅骨硬化性上皮样纤维肉瘤较为罕见,易转移、复发,影像学检查误诊率高,病理检查具有重要诊断作用,手术全切病灶,未行放化疗,未见复发迹象。Objective To explore the clinical features,imaging findings,pathological diagnosis and treatment of sclerosing epithelioid fibrosarcoma(SEF).Methods The clinical data of a patient with SEF of the skull were analyzed retrospectively,and the related literature were reviewed.Results This male patient,40 years old,showed continuous enlargement of mass on the head.CT examination of the skull showed that the left parietal bone was a near oval osteolytic lesion.Surgical resection was performed.During the operation,it was found that the tumor was located in the left parietal occipital part,fixed in the deep surface of the skull,with clear boundary and tough quality.It grew downward and compressed the brain tissue,and the adjacent dura was thickened.The lesion and affected dura were completely removed.Postoperative pathological examination showed SEF.No recurrence was found after 15 months of follow-up.Conclusion SEF of the skull is rare,the misdiagnosis rate of imaging examination is high,pathological examination plays an important role in diagnosis,and the effect of surgical resection is good.

关 键 词：硬化性上皮样纤维肉瘤 顶骨 颅骨 计算机断层扫描 磁共振成像 

分 类 号：R739.4[医药卫生—肿瘤]